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Abstract
Objectives
To compare the plasma levels of vitamin B12 and folic acid following resection of ileocecal or ileal segments used for orthotopic
bladder substitution.
Methods
Hemoglobin, hematocrit, and plasma levels of vitamin B12 and folic acid were measured in 34 patients with ileocecourethrostomy (ICUS) and
in 16 patients with ileal reservoir (IR), with a mean follow-up of 59.8 ± 41.9 months.
The results were compared with regard to both the type of operation and the length
of time since surgery.
Results
The level of folic acid was normal in all patients. The mean level of vitamin B12 in the ICUS group was 413.67 ± 160.45 ng/mL compared to 257.63 ± 121.36 for the IR
group. This difference was statistically significant. In the IR group, 18.75% of the
patients had a level of vitamin B12 below normal.
Conclusions
There is a tendency for vitamin B12 levels to fall in patients in whom the ileum is used. Resection of the ileocecal
segment including the junction does not alter the level of vitamin B12.
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Article info
Publication history
Accepted:
June 27,
1997
Received:
April 25,
1997
Identification
Copyright
© 1997 Elsevier Science Inc. all rights reserved. Published by Elsevier Inc.