ABSTRACT
Objective
To assess the incidence of genital pain in patients with urethral stricture and examine
the impact of urethroplasty. Genital pain is a common and challenging urological condition
and potentially associated with urethral stricture.
Methods
From 2011-2019, patients were offered enrollment in a prospective single-center study
assessing patient-reported genital pain pre- and 6-months posturethroplasty. Genital
pain was assessed with the question, “Do you experience genital (scrotum or penis)
pain?” answered on a five-point scale [“Never” (1), “Occasionally” (2), “Sometimes”
(3), “Most of the Time” (4) or “All of the Time” (5)]. Responses of 3, 4, or 5 were
considered clinically significant. Wilcoxon signed-rank test was used to compare pre-
and postoperative states and logistic regression was used to evaluate the association
between genital pain and clinical variables.
Results
Of the 387 patients completing enrollment, 36.4% (141/387) reported genital pain preoperatively.
Patients with panurethral stricture reported higher rates (57.1%) of pain (Odds Ratio
2.93, 95%CI 1.32-6.50; P = .008). Posturethroplasty, pain scores improved with an incidence of 14.2% (P < .0001). In patients reporting preoperative pain, 88.7% (125/141) experienced improvement,
8.5% were unchanged and 2.8% reported worsening pain. On logistic regression, patients
with penile strictures (O.R. 0.24, 95%CI 0.06-0.91; P = .04), hypospadias (O.R. 0.14, 95%CI 0.02-0.88; P = .04), and staged reconstruction (O.R. 0.22, 95%CI 0.05-0.90; P = .04) were less likely to report improvement.
Conclusion
Genital pain is common in patients with urethral stricture and improves in the majority
of patients undergoing urethroplasty but less so in patients with penile strictures,
hypospadias and staged reconstruction.
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Article Info
Publication History
Published online: November 04, 2022
Accepted:
October 9,
2022
Received:
September 6,
2022
Publication stage
In Press Journal Pre-ProofFootnotes
Conflict of Interest: None.
Disclosures: None.
Financial disclosure: Northern Alberta Urology Foundation.
Identification
Copyright
© 2022 Elsevier Inc. All rights reserved.
