Abstract
Objective
To determine the role of race in surgical outcomes of and complications after urethroplasty.
Methods
A single institution, retrospective review was conducted from 2011 to 2019 on male
patients ≥18 years of age who underwent urethroplasty. Exclusion criteria included
previous urethral cancer, lack of follow up, or revision urethroplasty. Failure of
urethroplasty was defined as requiring revision surgery or recurrence on imaging or
cystoscopy. Risk factors for recurrence were determined using descriptive statistics,
Wilcoxon comparisons, and multivariate logistic regression.
Results
Three hundred and seven patients were identified with 234 patients meeting inclusion
criteria. 63.2% identified as White/Caucasian (CA), 32.5% Black/African American (AA),
and 4.3% other race. Mean age was 49.4 years. Between CA and AA patients, there was
no difference in mean age, body mass index, smoking status, prior urethroplasty, or
prior dilation/DVIU. CAs were more likely to have a fossa navicularis stricture compared
to AAs (P = .0094), but there were no significant differences in bulbar, penile, or posterior
stricture rates (all P >.05) or length (P = .32). The overall stricture recurrence rate was 15.8% with a median of 242 days
to recurrence and no significant difference by race for either outcome (P = .83, P = .64). The only predictor of stricture recurrence was prior dilation/DVIU (P = .0404, OR 2.3, 95% CI 1.0, 5.6). Overall complication rate was 17.5%, with no difference
between CA and AAs rates (P = .83) or complication type (P = .62).
Conclusion
There was no significant difference in the rate of surgical failure for urethral stricture
repair based on race. The only predictor of surgical failure was having a prior urethral
dilation/DVIU.
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Article info
Publication history
Published online: November 28, 2021
Accepted:
October 19,
2021
Received:
March 3,
2021
Footnotes
Financial Disclosure: There are no financial conflicts of interest to disclose.
Funding Support: Research reported in this publication was supported by the National Center for Advancing Translational Sciences of the National Institutes of Health under award number UL1TR003096 and National Heart, Lung, and Blood Institute of National Institutes of Health under award number T35HL007473. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.
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