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Pediatric Case Reports| Volume 160, P199-202, February 2022

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Nephron-Sparing Approach For Familial Bilateral Synchronous Wilms Tumors

  • Victoria Turnbull
    Affiliations
    Michael G. DeGroote School of Medicine, McMaster University, Hamilton, Canada
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  • Harkanwal Randhawa
    Affiliations
    Division of Urology, McMaster University, Hamilton, Ontario, Canada
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  • Yuding Wang
    Affiliations
    Division of Urology, McMaster University, Hamilton, Ontario, Canada
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  • Melissa McGrath
    Affiliations
    McMaster Pediatric Surgery Research Collaborative, Department of Surgery, McMaster University, Hamilton, Ontario, Canada
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  • Luis H. Braga
    Correspondence
    Address correspondence to: Luis H. Braga, M.D., M.Sc., Ph.D., Department of Surgery, McMaster University, 1200 Main Street West, HHS, room 4E19, L8N 3Z5, Hamilton, Ontario, Canada.
    Affiliations
    Michael G. DeGroote School of Medicine, McMaster University, Hamilton, Canada

    Division of Urology, McMaster University, Hamilton, Ontario, Canada

    McMaster Pediatric Surgery Research Collaborative, Department of Surgery, McMaster University, Hamilton, Ontario, Canada

    Department of Health, Evidence and Impact, McMaster University, Hamilton, Ontario, Canada
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Published:November 06, 2021DOI:https://doi.org/10.1016/j.urology.2021.10.022

      Abstract

      Wilms tumors are the most common renal malignancy of childhood, often presenting as asymptomatic abdominal masses. These tumors can occur either in a unilateral or bilateral fashion, with bilateral tumors more commonly associated with various genetic syndromes and familial inheritance with some known loci. Bilateral tumors present challenges with regards to balancing oncologic control with renal function. Here, we present an unusual case of a young female patient diagnosed with bilateral Wilms tumors on the background of a strong family history and unknown genetic loci.
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