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Erectile Function Post Prostate Biopsy: A Systematic Review and Meta-analysis

  • Arihant Mehta
    Affiliations
    MRC Centre for Transplantation, Guy's Hospital Campus, King's College London, King's Health Partners, London, United Kingdom
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  • Whei Chang Kim
    Affiliations
    MRC Centre for Transplantation, Guy's Hospital Campus, King's College London, King's Health Partners, London, United Kingdom
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  • Karam Ghazal Aswad
    Affiliations
    MRC Centre for Transplantation, Guy's Hospital Campus, King's College London, King's Health Partners, London, United Kingdom
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  • Oliver Brunckhorst
    Affiliations
    MRC Centre for Transplantation, Guy's Hospital Campus, King's College London, King's Health Partners, London, United Kingdom
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  • Hashim U. Ahmed
    Affiliations
    Imperial Prostate, Division of Surgery, Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, London, United Kingdom

    Imperial Urology, Charing Cross Hospital, Imperial College Healthcare NHS Trust, London, United Kingdom
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  • Kamran Ahmed
    Correspondence
    Address correspondence to: Kamran Ahmed, M.B.B.S., M.R.C.S., Ph.D., F.R.C.S. Urol, Senior Clinical Lecturer, MRC Centre for Transplantation, King's College London, Guys Hospital, 5th Floor Southwark Wing, London SE1 9RT.
    Affiliations
    MRC Centre for Transplantation, Guy's Hospital Campus, King's College London, King's Health Partners, London, United Kingdom

    Department of Urology, King's College Hospital, London, United Kingdom
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Published:January 28, 2021DOI:https://doi.org/10.1016/j.urology.2021.01.035

      Abstract

      To determine the effect of prostate biopsy on erectile function we conducted a systematic review and meta-analysis up to August 2020. Mean difference of International Index of Erectile Function-5 compared to baseline scores were pooled at 1, 3 and 6-months using a random effect model. Of 47 full text articles identified, 7 were included in the meta-analysis. A significant reduction in mean IIEF5 of 4.61 (0.32-8.91, P= .04) was found at 1-month post biopsy. This resolved with non-significant differences at 3- and 6-months post procedure. Patients should be counselled regarding the transient effect on erectile function post biopsy.
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