Abstract
Objective
To evaluate differences in the incidence of benign ureteroenteric stricture, we compared
stricture rates of robot-assisted radical cystectomy (RARC) and open radical cystectomy
(ORC) using Surveillance, Epidemiology, and End Results-Medicare data.
Methods
We identified 332 RARC and 1449 ORC performed between 2009 and 2014 to determine stricture
rates at 6, 12, and 24 months following surgery. We defined ureteroenteric stricture
as the need for procedural intervention. Additionally, we compared the incidence of
stricture diagnosis. Multivariable proportional hazards regression was performed to
determine factors associated with stricture development.
Results
The incidence of ureteroenteric stricture at 6 and 12 months was higher for RARC vs
ORC at 12.1% vs 7.0% (P < .01) and 15.0% vs 9.5% (P = .01), respectively. RARC vs ORC stricture incidence at 2 years did not differ significantly
at 14.6% vs 11.4% (P = .29). Similarly, the stricture diagnosis rates were significantly lower following
ORC at 6, 12, and 24 months (P < .05). In adjusted analysis, RARC (HR 1.64, 95%CI 1.23-2.19) and preoperative hydronephrosis
(HR 1.51, 95% CI 1.17-1.94) were associated with the development of stricture. Higher
hospital volume was associated with a lower risk of stricture (HR 0.40, 95%CI 0.26-0.63).
Conclusion
RARC is associated with a higher rate of ureteroenteric stricture diagnosis and intervention
on a population-based level that is mitigated by higher hospital volume. A significant
study limitation is inability to differentiate extracorporeal vs intracorporeal diversion.
However, a stricture complication compounds the financial burden of care and efforts
must be pursued to improve this surgical outcome.
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References
- Comparative analysis of outcomes and costs following open radical cystectomy versus robot-assisted laparoscopic radical cystectomy: results from the US Nationwide Inpatient Sample.Eur Urol. 2012; 61: 1239-1244
- Randomized trial comparing open radical cystectomy and robot-assisted laparoscopic radical cystectomy: oncologic outcomes.Eur Urol. 2018; 74: 465-471
- Long-term oncologic outcomes following robot-assisted radical cystectomy: results from the International Robotic Cystectomy Consortium.Eur Urol. 2015; 68: 721-728
- Systematic review and cumulative analysis of perioperative outcomes and complications after robot-assisted radical cystectomy.Eur Urol. 2015; 67: 376-401
- Ureteroenteric strictures after open radical cystectomy and urinary diversion: the university of southern california experience.Urology. 2015; 86: 87-91
- Long-term complications of conduit urinary diversion.J Urol. 2011; 185: 562-567
- Getting out of a tight spot: an overview of ureteroenteric anastomotic strictures.Nat Rev Urol. 2016; 13: 447-455
- Overview of the SEER-Medicare data: content, research applications, and generalizability to the United States elderly population.Med Care. 2002; 40 (IV–3)
- Comorbidity measures for use with administrative data.Med Care. 1998; 36: 8-27
- Management of ureteroenteric stricture: predictive modeling to compare cost.J Endourol. 2016; 30: 1244-1251
- Comparative effectiveness of robot-assisted vs. open radical cystectomy.Urol Oncol. 2018; 36: 88.e1-88.e9
- Robot-assisted radical cystectomy versus open radical cystectomy in patients with bladder cancer (RAZOR): an open-label, randomised, phase 3, non-inferiority trial.Lancet. 2018; 391: 2525-2536
- Comparing open radical cystectomy and Robot-assisted laparoscopic radical cystectomy: a randomized clinical trial.Eur Urol. 2015; 67: 1042-1050
- Critical analysis of hospital readmission and cost burden after Robot-assisted radical cystectomy.J Endourol. 2016; 30: 83-91
- The impact of running versus interrupted anastomosis on ureterointestinal stricture rate after radical cystectomy.J Urol. 2013; 190: 923-927
- Ureteroenteric anastomotic strictures after radical cystectomy-does operative approach matter?.J Urol. 2013; 189: 541-547
- Ureteral stents placed at the time of urinary diversion decreases postoperative morbidity.Urol Int. 2012; 88: 66-70
- Robotic intracorporeal orthotopic neobladder during radical cystectomy in 132 patients.J Urol. 2014; 192: 1734-1740
- Preoperatively dilated ureters are a specific risk factor for the development of ureteroenteric strictures after open radical cystectomy and Ileal neobladder.J Urol. 2017; 198: 1098-1106
- Is continent cutaneous urinary diversion a suitable alternative to orthotopic bladder substitute and ileal conduit after cystectomy?.BJU Int. 2015; 116: 805-814
- Natural history, predictors and management of ureteroenteric strictures after Robot assisted radical cystectomy.J Urol. 2017; 198: 567-574
- The learning curve of robot-assisted radical cystectomy: results from the International robotic cystectomy consortium.Eur Urol. 2010; 58: 197-202
- Robot-assisted radical cystectomy (RARC) with intracorporeal neobladder - what is the effect of the learning curve on outcomes?.BJU Int. 2014; 113: 100-107
- Outcomes of intracorporeal urinary diversion after Robot-assisted radical cystectomy: results from the International robotic cystectomy consortium.J Urol. 2017; 188: 1302-1311
- Best practices in robot-assisted radical cystectomy and urinary reconstruction: recommendations of the Pasadena Consensus Panel.Eur Urol. 2015; 67: 363-375
- Robotic intracorporeal orthotopic ileal neobladder: replicating open surgical principles.Eur Urol. 2012; 62: 891-901
- Updates on robotic intracorporeal urinary diversions.Curr Urol Rep. 2018; 19: 28
- Use of indocyanine green to minimise uretero-enteric strictures after robotic radical cystectomy.BJU Int. 2019; 124: 302-307
Article info
Publication history
Published online: October 13, 2019
Accepted:
July 18,
2019
Received:
January 6,
2019
Footnotes
Funding: Supported by The Frederick J. and Theresa Dow Wallace Fund of the New York Community Trust.
Identification
Copyright
© 2019 Elsevier Inc. All rights reserved.