Abstract
Objective
To compare the utility of generic health quality of life (QOL) and condition specific
indicators as patient reported outcomes measures for urethral stricture surgery.
Materials and Methods
Patient data were obtained from the Trauma and Urologic Reconstructive Network of
Surgeons collaborative database. Patients who underwent any successful urethroplasty
and completed both pre- and postoperative generic and condition-specific questionnaires
were included.
Results
A total of 201 patients met inclusion criteria. Urethral-stricture specific measures
improved after surgery: mean LUTS score (13.1-4.0, p<0.05), Peeling curve (3.1-1.7,
p < 0.05), and overall interference of urinary symptoms on life (3.0-1.6, p < 0.05).
Mean overall health status visual analog scale (74.2-80.0, p < 0.05) and generic health
QOL EQ-5D index scores (0.90-0.95, p < 0.05) also improved; however, individual EQ-5D
measures assessing mobility, self-care, and activity level did not change. EQ-5D measures
for pain/discomfort (1.48-1.23, p < 0.05) and anxiety/depression (1.33-1.21, p < 0.05)
improved, but not to the same extent as stricture-specific measures. More patients
reported improvement in condition-specific urethra/penis pain and bladder pain compared
to improvement in generic EQ-5D pain/discomfort (p < 0.001).
Conclusion
Generic health QOL indicators are less meaningful in the assessment of urethral stricture
surgery and should be replaced with condition-specific outcomes measures. It is important
to ensure that appropriate condition-specific outcomes measures are utilized as patient
reported outcomes measures become more prevalent in medicine and potentially become
utilized to evaluate surgeon outcomes and determine surgeon reimbursement.
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References
- Stricture recurrence after urethroplasty: a systematic review.J Urol. 2009; 182: 1266-1270
- Measuring and predicting patient dissatisfaction after anterior urethroplasty using patient reported outcomes measures.J Urol. 2016; 196: 453-461
- Development and evaluation of an abridged, 5-item version of the International Index of Erectile Function (IIEF-5) as a diagnostic tool for erectile dysfunction.Int J Impot Res. 1999; 11: 319-326
- Male Sexual Health Questionnaire (MSHQ): scale development and psychometric validation.Urology. 2004; 64: 777-782
- Defining a patient-reported outcome measure for urethral stricture surgery.Eur Urol. 2011; 60: 60-68
- Development and preliminary testing of the new five-level version of EQ-5D (EQ-5D-5L).Qual Life Res. 2011; 20: 1727-1736
- A prospective patient-centred evaluation of urethroplasty for anterior urethral stricture using a validated patient-reported outcome measure.Eur Urol. 2013; 64: 777-782
- Diagnostic assessment of benign prostatic hyperplasia.Prostate Suppl. 1989; 2: 51-68
- The values and value of patient-centered care.Ann Fam Med. 2011; 9: 100-103
- Quality criteria were proposed for measurement properties of health status questionnaires.J Clin Epidemiol. 2007; 60: 34-42
- Patient-Reported Outcome Measures in Urethral Reconstruction.Curr Urol Rep. 2018; 19: 48
- The American Urological Association symptom score in the evaluation of men with lower urinary tract symptoms: at 2 years of followup, does it work?.J Urol. 1996; 155: 1971-1974
- Prospective evaluation of the American Urological Association symptom index and peak urinary flow rate for the followup of men with known urethral stricture disease.J Urol. 2002; 168: 2051-2054
- American Urological Association symptom index in the assessment of urethroplasty outcomes.J Urol. 1998; 159: 1192-1194
- Presenting symptoms of anterior urethral stricture disease: a disease specific, patient reported questionnaire to measure outcomes.J Urol. 2012; 187: 559-562
- The International Prostate Symptom Score (IPSS) is an inadequate tool to screen for urethral stricture recurrence after anterior urethroplasty.Urology. 2016; 95: 197-201
- Patient satisfaction with the outcome of surgery for urethral stricture.J Urol. 2002; 167: 2507-2511
- Comprehensive qualitative assessment of urethral stricture disease: toward the development of a patient centered outcome measure.J Urol. 2017; 198: 1113-1118
Article info
Publication history
Published online: December 20, 2018
Accepted:
December 11,
2018
Received:
November 15,
2018
Footnotes
Funding Support: None.
Disclosures: None.
Identification
Copyright
© 2018 Elsevier Inc. All rights reserved.