Objective
To create a simple neobladder and determine whether the double-limb U-Pouch (D-LUP)
has the same capacity and compliance as a Studer or Camey I neobladder. To develop
an orthotopic diversion that can be applied to robotic surgery with laboratory data
supporting the concept.
Materials and Methods
Kidneys, ureters, bladders, and small intestine were obtained from pigs at the time
of scheduled autopsy after completion of institutionally approved investigational
trauma protocols. A Camey I neobladder, spherical neobladder, and D-LUP, were constructed
from 40-cm segments of small intestine. They were compared for capacity, compliance,
and pouch-to-urethra anastomotic distance.
Results
The cystometric capacity at 30 cm H2O for the Camey I, Studer, and D-LUP neobladders
were 250 mL, 350 mL, and 430 mL, respectively. The pouch-to-urethra anastomotic distance
was 0 cm for the Camey I, 10 cm for the spherical reservoir, and 0 cm for the D-LUP.
Compliance was 10 mL/cm H20 for the Camey 1, 15 mL/cm H2O for the sphere, and 16 mL/cm
H20 for the D-LUP.
Conclusion
The D-LUP neobladder was simple to construct, had a more dependent ileo-urethrostomy
site, larger capacity, and similar compliance when compared with a spherical neobladder.
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Article info
Publication history
Published online: December 01, 2017
Accepted:
November 21,
2017
Received:
October 25,
2017
Footnotes
Financial Disclosure: The authors declare that they have no relevant financial interests.
Identification
Copyright
Published by Elsevier Inc.