Objective
To evaluate patient-reported temporal changes in penile curvature, pain, shortening,
sexual function, and quality of life in men undergoing conservative treatment for
PD.
Materials and Methods
Of 3840 patients who underwent evaluation at our institution between 1990 and 2012,
719 were randomly selected to receive a mail-in questionnaire with topics including
penile curvature, pain, shortening, sexual function, and quality of life. Men endorsing
prior intralesional or surgical therapy were excluded.
Results
A total of 125 patients completed the survey and met the inclusion criteria. The median
duration between onset of PD symptoms and survey completion was 8.4 years. Overall,
38% felt that their condition had overall improved and 26% felt that their condition
had worsened since onset. Penile curvature resolved in 43%, remained stable in 37%,
and worsened in 20%. Twelve percent of the men developed a second de novo curvature.
Penile pain occurred in 42%, among whom the pain worsened in 18% and completely resolved
in 64%. Sixty-five percent reported penile shortening. Subjective erectile function
decreased in 60%, and >40% experienced difficulties with penetrative intercourse.
Sexual frequency decreased in 68% of the patients and 59% reported decreased relationship
satisfaction. Approximately 50% described negative psychological impacts on self-esteem
and image.
Conclusion
The current report provides the most comprehensive and longest-term data on patient-reported
outcomes in men undergoing nonsurgical and noninjection therapies. Although approximately
40% of the men reported overall and curvature improvement at a median 8.4-year follow-up,
penile length loss, worsening sexual function, relationship dissatisfaction, and psychosocial
distress occurred in the majority of PD men.
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Article info
Publication history
Published online: November 21, 2017
Accepted:
November 9,
2017
Received:
September 25,
2017
Footnotes
Financial Disclosure: The authors declare that they have no relevant financial interests.
Identification
Copyright
© 2017 Elsevier Inc. All rights reserved.
