Advertisement

Clinical Efficacy of 1-Year Intensive Systematic Dietary Manipulation as Complementary and Alternative Medicine Therapies on Female Patients With Interstitial Cystitis/Bladder Pain Syndrome

  • Hitoshi Oh-oka
    Correspondence
    Address correspondence to: Hitoshi Oh-oka, Ph.D., M.D., Department of urology, Kobe Medical Center, 3-1-1, Nishiochiai, Suma-ku, Kobe-shi, Hyogo 654-0155, Japan.
    Affiliations
    Department of Urology, National Hospital Organization, Kobe Medical Center, Kobe, Hyogo, Japan
    Search for articles by this author

      Objective

      To evaluate the clinical efficacy of intensive systematic dietary manipulation (ISDM) for female patients with interstitial cystitis (IC)/bladder pain syndrome (BPS) in stable condition who were followed up in our hospital.

      Materials and Methods

      In cooperation with the nutrition control team, we created a basic IC/BPS diet menu for 1 month. Data regarding daily food intake and food-related symptoms were collected by conducting a detailed interview of each patient, and we set meal menu to control IC/BPS symptoms and advised the patients to reduce the intake of specific food items to the maximum possible extent. The following food items were removed from or restricted in the diet of patients: tomatoes, tomato products, soybean, tofu product, spices, excessive potassium, citrus, high-acidity-inducing substances, etc. We evaluated the following factors 3 months and 1 year after the start of the intervention: O'Leary-Sant symptom index, O'Leary-Sant problem index, urgency visual analogue scale score, bladder or pelvic pain visual analogue scale score, and numerical patient-reported quality of life index.

      Results

      All evaluated factors improved statistically significantly when the intensive group was compared with the nonintensive group (baseline to 3 months and 3 months to 1 year ISDM, P <.05, respectively).

      Conclusion

      ISDM was found to alleviate the symptoms of IC/BPS in almost 3 months and continued clinical efficacy for at least 1 year. ISDM as one of the conservative treatment modality for IC/BPS should be attempted more strictly because of its noninvasiveness, without alterations to the other treatments.
      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'

      Subscribe:

      Subscribe to Urology
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect

      References

        • Goldman H.B.
        Interstitial cystitis—the great enigma.
        J Urol. 2000; 164: 1921
        • Homma Y.
        • Ueda T.
        • Ito T.
        • et al.
        Japanese guideline for diagnosis and treatment of interstitial cystitis.
        Int J Urol. 2009; 16: 4-16
        • Seth A.
        • Teichman J.M.
        What's new in the diagnosis and management of painful bladder syndrome/interstitial cystitis?.
        Curr Urol Rep. 2008; 9: 349-357
        • Homma Y.
        • Ueda T.
        • Ito T.
        • et al.
        Interstitial cystitis. Diagnosis and treatment-1.
        in: Guideline Committee of the Society of Interstitial Cystitis in Japan Interstitial Cystitis Guidelines. 1st ed. Blackwell Publishing, Tokyo2007: 20-32 (33-37)
        • O'Hare 3rd, P.G.
        • Hoffmann A.R.
        • Allen P.
        • et al.
        Interstitial cystitis patients' use and rating of complementary and alternative medicine therapies.
        Int Urogynecol J. 2013; 24: 977-982
        • Quillin R.B.
        • Erickson D.R.
        Practical use of the new American Urological Association interstitial cystitis guidelines.
        Curr Urol Rep. 2012; 13: 394-401
        • Hanno P.M.
        • Wein A.J.
        Conservative therapy of interstitial cystitis.
        Semin Urol. 1991; 9: 143-147
        • Kasuga M.
        • Sasaki S.
        • Shibata K.
        • et al.
        Scientific Committee of Dietary Reference Intakes for Japanese Dietary Reference Intakes for Japanese. 1st ed. Daiichi Shuppan, Tokyo2009: 43-109 (2010)
        • Hanno P.M.
        • Erickson D.
        • Moldwin R.
        • et al.
        Diagnosis and treatment of interstitial cystitis/bladder pain syndrome: AUA guideline amendment.
        J Urol. 2015; 193: 1545-1553
        • Engeler D.S.
        • Baranowski A.P.
        • Dinis-Oliveira P.
        • et al.
        The 2013 EAU guidelines on chronic pelvic pain: is management of chronic pelvic pain a habit, a philosophy, or a science? 10 years of development.
        Eur Urol. 2013; 64: 431-439
        • Cox A.
        • Golda N.
        • Nadeau G.
        • et al.
        CUA guideline: diagnosis and treatment of interstitial cystitis/bladder pain syndrome.
        Can Urol Assoc J. 2016; 10: E136-E155
        • Friedlander J.I.
        • Shorter B.
        • Moldwin R.M.
        Diet and its role in interstitial cystitis/bladder pain syndrome (IC/BPS) and comorbid conditions.
        BJU Int. 2012; 109: 1584-1591
        • Clemens J.Q.
        • Brown S.O.
        • Kozloff L.
        • et al.
        Predictors of symptom severity in patients with chronic prostatitis and interstitial cystitis.
        J Urol. 2006; 175: 963-966
        • Yamada T.
        Significance of complications of allergic diseases in young patients with interstitial cystitis.
        Int J Urol. 2003; 10: S56-S58
        • van de Merwe J.P.
        • Nordling J.
        • Bouchelouche P.
        • et al.
        Diagnostic criteria, classification, and nomenclature for painful bladder syndrome/interstitial cystitis: an ESSIC proposal.
        Eur Urol. 2008; 53: 60-67
        • Theoharides T.C.
        • Sant G.R.
        Immunomodulators for treatment of interstitial cystitis.
        Urology. 2005; 65: 633-638
        • Parsons C.L.
        • Lilly J.D.
        • Stein P.
        Epithelial dysfunction in nonbacterial cystitis (interstitial cystitis).
        J Urol. 1991; 145: 732-735
        • FitzGerald M.P.
        • Payne C.K.
        • Lukacz E.S.
        • et al.
        Randomized multicenter clinical trial of myofascial physical therapy in women with interstitial cystitis/painful bladder syndrome and pelvic floor tenderness.
        J Urol. 2012; 187: 2113-2118