Pediatric Urology| Volume 104, P172-174, June 2017

Iatrogenic Fibroepithelial Polyps in Children With Hydronephrosis

Published:February 13, 2017DOI:


      To discover the possible factor of the iatrogenic fibroepithelial polyps (FEPs).

      Materials and Methods

      A retrospective chart review of 28 pediatric patients who have undergone pyeloplasties for ureteropelvic junction obstruction with pathologically proven FEPs was performed from January 2009 to June 2016 at our hospital. Among them, 6 patients without apparent FEPs at the time of the first pyeloplasty were found to have FEPs at the time of reoperation. The medical history and clinical, diagnostic, intraoperative, pathologic, and follow-up data of the 6 patients were reviewed.


      All iatrogenic FEPs were located proximal to the anastomotic stoma. On pathological examination, the size of the FEPs ranged from 1.5 to 3.5 cm. The FEPs were pink, grayish-white, or tan-gray in color and cauliflower-like in shape. Microscopically, they arose from the submucosa and consisted of a layer of normal transitional epithelium covering a fibrovascular stromal core showing sparse vascularity and prominent edema. The mean follow-up period was 47 months (range, 4-82 months). All patients' symptoms disappeared and the function of the affected kidney was preserved after the second pyeloplasty. No patients developed FEP recurrence.


      Nephrostomy may associate with iatrogenic FEPs in young children. Iatrogenic FEPs are a specific type of polyp that grows rapidly within a very short time. Pathologically, iatrogenic FEPs are the same as other types of FEPs.
      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'


      Subscribe to Urology
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect


        • Adey G.S.
        • Vargas S.O.
        • Retik A.B.
        • et al.
        Fibroepithelial polyps causing ureteropelvic junction obstruction in children.
        J Urol. 2003; 169: 1834-1836
        • Niu Z.B.
        • Yang Y.
        • Hou Y.
        • et al.
        Ureteral polyps: an etiological factor of hydronephrosis in children that should not be ignored.
        Pediatr Surg Int. 2007; 23: 323-326
        • Bian Z.
        • Liu X.
        • Hua Y.
        • et al.
        Laparoscopic management of multiple ureteral polyps in children.
        J Urol. 2011; 186: 1444-1449
        • Wang X.M.
        • Jia L.Q.
        • Wang Y.
        • et al.
        Utilizing ultrasonography in the diagnosis of pediatric fibroepithelial polyps causing ureteropelvic junction obstruction.
        Pediatr Radiol. 2012; 42: 1107-1111
        • Eilenberg J.
        • Seery W.
        • Cole A.
        Multiple fibroepithelial polyps in the pediatric age group: case report.
        J Urol. 1977; 117: 793
        • Thorup J.
        • Pedersen P.V.
        • Clausen N.
        Benign ureteral polyp as a cause of intermittent hydronephrosis in a child.
        J Urol. 1981; 126: 796-797
        • Mydlo J.
        • Reda E.
        • Gill B.
        • et al.
        Fibroepithelial polyp in a child.
        Urology. 1988; 31: 318-320
        • Zeman L.
        • Dusek M.
        • Lisy J.
        • et al.
        Multiple fibroepithelial polyps of the upper ureter in a 17-year-old boy–case report and review of the literature.
        Eur J Pediatr Surg. 2004; 14: 358-361
        • Liddell R.M.
        • Weinberger E.
        • Schofield D.E.
        • et al.
        Fibroepithelial polyp of the ureter in a child.
        AJR Am J Roentgenol. 1991; 157: 1273-1274
        • Cassar Delia E.
        • Joseph V.T.
        • Sherwood W.
        Fibroepithelial polyps causing ureteropelvic junction obstruction in children—a case report and review article.
        Eur J Pediatr Surg. 2007; 17: 142-146
        • Kara C.
        • Reşorlu B.
        • Oğuz U.
        • et al.
        Incidentally detected ureteral fibroepithelial polyps in children: is endoscopic treatment of them really necessary?.
        Int Urol Nephrol. 2010; 42: 1-5
        • Williams T.R.
        • Wagner B.J.
        • Corse W.R.
        • et al.
        Fibroepithelial polyps of the urinary tract.
        Abdom Imaging. 2002; 27: 217-221
        • Lam J.S.
        • Bingham J.B.
        • Gupta M.
        Endoscopic treatment of fibroepithelial polyps of the renal pelvis and ureter.
        Urology. 2003; 62: 810-813