Dextranomer/hyaluronic acid copolymer (Deflux) first received Food and Drug Administration
approval in 2001 for endoscopic injection in children with grade II-IV vesicoureteral
reflux VUR. As experience has grown, Deflux has been used more liberally with encouraging
results. We report 3 cases where Deflux was used in off-label fashion, resulting in
delayed ureteral obstruction and loss of renal function (range 18-52 months postoperatively).
We now place increased emphasis on the need for long-term follow-up after Deflux in
both routine and complex cases, particularly in situations of off-label use.
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Article info
Publication history
Published online: September 26, 2016
Accepted:
September 7,
2016
Received:
June 9,
2016
Footnotes
Financial Disclosure: The authors declare that they have no relevant financial interests.
Identification
Copyright
© 2016 Elsevier Inc. All rights reserved.
