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Financial Disclosure: The authors declare that they have no relevant financial interests.
Funding Support: This project was supported by research grants from the Public Health Service, National Institutes of Health (DK58859, AR30582, and 1UL1 RR024150-01), and Merck Research Laboratories.
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- Editorial CommentUrologyVol. 82Issue 6
- PreviewIn recent years, new prostate-specific antigen (PSA) testing guidelines from various professional organizations have sparked controversy, as there is a divergence of opinions on the usefulness of PSA. Panels formulating these guidelines rely heavily on randomized clinical trials and statistical modeling studies of trial data, whereas frequently ignoring compelling evidence from other sources. In addition, independent panels have formulated widely varying recommendations from the same body of evidence.