Objectives
To investigate whether voiding dysfunction (VD) in children with attention deficit
hyperactivity disorder (ADHD) could be treated successfully using individualized therapy.
We also sought to describe the spectrum of voiding symptoms experienced by children
with ADHD. ADHD is diagnosed in 3-5% of children. These children have a greater incidence
of VD than non-ADHD controls, and it is less amenable to treatment.
Methods
A comprehensive history assessed the nature of the voiding disorder. A physical examination,
screening urologic ultrasonography, and urinalysis were routinely performed, with
electromyography combined with uroflowmetry performed for certain cases. Treatment
was individualized to include behavioral modification, bowel and diet management,
biofeedback, pharmacotherapy, and close follow-up.
Results
A total of 75 children with ADHD were referred because of VD. The 75 children (39
boys and 36 girls) were 5-16 years old. Of the 75 children, 60 were taking medication
for ADHD. All the children had daytime wetting (>1/d, 5-7 d/wk) and urgency. In addition,
88% had frequency and 87% had sleep enuresis. Of the 75 families, 56 proceeded with
our prescribed program. Of the 56 children, 47 (83.9%) had complete resolution or
improvement of the daytime symptoms. Of the 17 patients (30.4%) with complete resolution,
9 responded to behavior modification and anticholinergics and 8 needed biofeedback.
Of the 30 patients with a partial response (53.6%), 9 responded to behavior modification
alone, 15 to behavior modification and anticholinergics, and 6 required all 3 modalities.
Of the 56 children, 9 failed to respond to any of the 3 modalities.
Conclusions
Diurnal symptoms constituted the most common referred complaint in children with ADHD.
VD can be successfully treated if the treatment is individualized. Multimodal treatment,
including behavior modification combined with anticholinergic agents and/or biofeedback,
appears to be effective in managing VD in most of these challenging cases.
To read this article in full you will need to make a payment
Purchase one-time access:
Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online accessOne-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
Subscribe:
Subscribe to UrologyAlready a print subscriber? Claim online access
Already an online subscriber? Sign in
Register: Create an account
Institutional Access: Sign in to ScienceDirect
References
- Clinical practice guidelines: diagnosis and management of the child with attention deficit/hyperactivity disorder.Pediatrics. 2000; 105: 1158-1170
- A survey of voiding dysfunction in children with attention deficit-hyperactivity disorder.J Urol. 2003; 170: 1521-1523
- Attention-deficit/hyperactivity disorder (ADHD) as a risk factor for persistent nocturnal enuresis in children: a two-year follow-up study.Acta Paediatr. 2005; 94: 1619-1625
- Management of urinary incontinence and nocturnal enuresis in attention-deficit hyperactivity disorder.J Urol. 2003; 170: 1347-1350
- Diagnostic and Statistical Manual, IV.American Psychiatric Association, Arlington, VA2000
- Attention deficit hyperactivity disorder.EMed WebMD. 2008; 28: 82-91
- Attention-deficit/hyperactivity disorder: a selective overview.Biol Psychiatry. 2005; 57: 1215-1220
- Health-related quality of life in children and adolescents who have a diagnosis of attention-deficit/hyperactivity disorder.Pediatrics. 2004; 114: e541-e547
- Attention deficit/hyperactivity disorder in children with nocturnal enuresis.J Urol. 2004; 171: 2576-2579
- Animated biofeedback yields more rapid results than non-animated biofeedback in the treatment of dysfunctional voiding in the pediatric population.J Urol. 2008; 180: 300-305
- Office management of pediatric primary nocturnal enuresis: a comparison of physician advised and parent chosen alternative treatment options.J Urol. 2007; 178: 1758-1761
- High-intensity short-term biofeedback in children with Hinman's syndrome (non-neuropathic voiding dyssynergia).J Pediatr Urol. 2006; 2: 344-350
- Treatment of nocturnal enuresis in children with attention deficit hyperactivity disorder.J Urol. 2007; 178: 1744-1747
- Prepulse inhibition of startle and the neurobiology of primary nocturnal enuresis.Biol Psychiatry. 1999; 45: 1455-1466
- What is attention-deficit/hyperactivity disorder?.Pediatr Clin North Am. 1999; 46: 831-843
- Development of a symptom score for dysfunctional elimination syndrome.J Urol. 2009; 182: 1939-1943
- Dysfunctional voiding and incontinence scoring system: quantitative evaluation of incontinence symptoms in pediatric population.J Urol. 2005; 173: 969-973
- The dysfunctional voiding scoring system: quantitative standardization of dysfunctional voiding symptoms in children.J Urol. 2000; 164: 1011-1015
Article info
Publication history
Published online: March 29, 2010
Accepted:
January 18,
2010
Received:
November 30,
2009
Identification
Copyright
© 2010 Elsevier Inc. Published by Elsevier Inc. All rights reserved.