This is an excellent clinical review of a large number of patients who underwent transrectal
ultrasound-guided prostate biopsy (TRUS-BP) during an almost 5-year period. All patients
received ciprofloxacin, 500 mg twice daily for 5 days, starting 24 hours before the
procedure. All patients underwent a minimum of a 12-core biopsy. The authors reviewed
the infectious complications and noted that these occurred in 28 of 1339 patients
(2.1%). A slightly greater (and statistically significant) incidence was found in
patients undergoing repeat biopsy (6.8%) vs an initial biopsy (1.3%). Most of the
patients (61%) had Escherichia coli as the cause of the infection, with 13 of 17 (76.5%) caused by extended-spectrum
β-lactamase (ESBL)-producing bacteria. Of these, 10 of 17 (58.9%) were due to ESBL-producing
E. coli. These infections were resistant to fluoroquinolone antibiotics.
To read this article in full you will need to make a payment
Purchase one-time access:
Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online accessOne-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
Subscribe:
Subscribe to UrologyAlready a print subscriber? Claim online access
Already an online subscriber? Sign in
Register: Create an account
Institutional Access: Sign in to ScienceDirect
References
- Single dose levofloxacin prophylaxis for prostate biopsy in patients at low risk.J Urol. 2002; 168: 1021-1023
- Empirical management of urinary tract infections complicating transrectal ultrasound guided prostate biopsy.J Urol. 2003; 169: 1762-1765
- Transrectal ultrasound guided biopsy of the prostate: do enemas decrease clinically significant complications?.J Urol. 2001; 166: 82-85
- The incidence of fluoroquinolone resistant infections after prostate biopsy—are fluoroquinolones still effective prophylaxis?.J Urol. 2008; 179: 952-955
American Urological Association Education and Research. Antibiotic Prophylaxis. Bethesda: American Urological Association Education and Research, Incorporated; Revised July, 2008.
Article info
Identification
Copyright
© 2009 Elsevier Inc. Published by Elsevier Inc. All rights reserved.
