To evaluate the possible relationship between the sexual and psychiatric status of premenopausal female patients with fibromyalgia compared with healthy controls.
A total of 48 female patients with fibromyalgia and 38 age-matched healthy controls were enrolled in the study. All the subjects were asked to complete the Female Sexual Function Index (FSFI) for sexual status and the State-Trait Anxiety Inventory (STAI) and Beck Depression Inventory (BDI) for psychiatric assessment. Serum biochemical analysis was done, and the serum hormonal levels were analyzed.
The mean BDI score for patients was significantly greater than the score for the controls (P = 0.017) and the mean FSFI score was significantly lower than the score for the controls (P = 0.001). According to the FSFI data, female sexual dysfunction was found in 26 patients (54.2%) with fibromyalgia and only 6 controls (15.8%), a significant difference (Pearson chi-square = 14.46, P = 0.000). When the subscores of each domain of FSFI were evaluated, the most common sexual problem was diminished desire in patients (n = 30, 62.5%) and controls (n = 11, 28.9%). In the correlation analysis, the FSFI score showed a significant negative correlation with the BDI (r = −0.337, P = 0.002) and STAI (r = −0.413, P = 0.004) scores. No significant correlation was revealed between the FSFI and BDI or FSFI and STAI scores in the controls.
Depression is one of the emotional disorders commonly encountered in women with fibromyalgia, most possibly leading to sexual dysfunction. Thus, sexual dysfunction related to impaired psychiatric status should be considered a common problem in premenopausal women with fibromyalgia.
To read this article in full you will need to make a payment
Purchase one-time access:Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
One-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
Subscribe:Subscribe to Urology
Already a print subscriber? Claim online access
Already an online subscriber? Sign in
Register: Create an account
Institutional Access: Sign in to ScienceDirect
- Female sexual dysfunction.Urol Clin North Am. 2001; 28: 405-416
- Biology of female sexual function.Urol Clin North Am. 2002; 29: 685-693
- Sexual dysfunction in the United States.JAMA. 1999; 281: 537-544
- Histomorphometric analysis of age-related structural changes in human clitoral cavernosal tissue.J Urol. 1999; 161: 940-944
- Incidence and prevalence of the sexual dysfunctions.Arch Sex Behav. 1990; 19: 389-408
- Normal human sexuality and sexual and gender identity disorders.in: Sadock B.J. Sadock V.A. Comprehensive Textbook of Psychiatry. Lippincott Williams & Wilkins, Philadelphia2000: 1577-1662
- Report of the International Consensus Development Conference on Female Sexual Dysfunction.J Urol. 2000; 163: 888-893
- Clinical characteristics and biopathophysiological mechanisms of fibromyalgia syndrome.in: Baldry P. Myofascial Pain and Fibromyalgia Syndromes A Clinical Guide to Diagnosis and Management. Churchill Livingstone, Edinburgh2001: 351-377
- Fibromyalgia syndrome.in: Rachlin E.S. Rachlin I. Myofascial Pain and Fibromyalgia Trigger Point Management. Mosby, Philadelphia2002: 3-31
- Fibromyalgia-symptom or diagnosis.Scand J Rheumatol Suppl. 2000; 113: 3-7
- The prevalence of musculoskeletal pain and fibromyalgia in patients hospitalized on internal medicine wards.Semin Arthritis Rheum. 2001; 30: 411-417
- Personality assessment.in: Sadock B.J. Sadock V.A. Comprehensive Textbook of Psychiatry. Lippincott Williams & Wilkins, Philadelphia2000: 702-722
- The Female Sexual Dysfunction Index (FSFI).J Sex Marital Ther. 2000; 26: 191-208
- The prevalence of female sexual dysfunction and potential risk factors that may impair sexual dysfunction in Turkish women.Urol Int. 2004; 72: 52-57
- Regional myofascial pain syndromes.Rheum Dis Clin North Am. 1989; 15: 31-44
- Assessment of sexual satisfaction in fibromyalgia patients.Einstein. 2004; 2: 177-181
- Fibromyalgia and major affective disorder.Am J Psychiatry. 1985; 142: 441-446
- Affective spectrum disorder.Am J Psychiatry. 1990; 147: 552-564
- Psychological aspects of fibromyalgia syndrome.Baillieres Clin Rheumatol. 1994; 8: 811-837
- Fibromyalgia, physical activity, and daily functioning.Arthritis Care Res. 2000; 13: 343-351
- The emotional aspects of pain.in: Baldry P. Myofascial Pain and Fibromyalgia Syndromes A Clinical Guide to Diagnosis and Management. Churchill Livingstone, Edinburgh2001: 45-55
- Biological and psychological factors associated with memory function in fibromyalgia syndrome.Health Psychol. 2003; 22: 592-597
- Assessing depression among persons with chronic pain using the Center for Epidemiological Studies-Depression Scale and the Beck Depression Inventory.Clin J Pain. 1997; 13: 163-170
- Psychiatric disorders in patients with fibromyalgia.Psychosomatics. 1999; 40: 57-63
- Hypothalamic-pituitary-adrenal axis perturbations in patients with fibromyalgia.Arthritis Rheum. 1994; 37: 1583-1592
- Glucocorticoid receptors, fibromyalgia and low back pain.Psychoneuroendocrinology. 1997; 22: 603-614
- A naturalistic evaluation of cortisol secretion in persons with fibromyalgia and rheumatoid arthritis.Arthritis Care Res. 2000; 13: 51-61
- Prevalence of sexual dysfunction in women.J Sex Marital Ther. 1993; 19: 171-178
- Concentration and memory deficits in patients with fibromyalgia syndrome.J Clin Exp Neuropsychol. 1999; 21: 477-487
- Cognitive dysfunction in fibromyalgia.Curr Rheumatol Rep. 2001; 3: 123-127
- Etiological correlates of vaginismus.J Sex Marital Ther. 2003; 29: 47-59
- Characteristics of women with vulvar pain disorders.J Sex Marital Ther. 2003; 29: 45-58
- Women’s sexual dysfunction.Can Med Assoc J. 2005; 10: 1327-1333
Accepted: August 3, 2005
Received: May 5, 2005
© 2006 Elsevier Inc. Published by Elsevier Inc. All rights reserved.