Abstract
Objectives
To evaluate the effects of prostatic massage on the serum complexed PSA (cPSA) concentration
in various prostatic diseases.
Methods
A total of 51 men who presented to our outpatient clinic for the first time with symptoms
of lower urinary outflow obstruction were included in this study. Blood samples were
obtained from each patient before and 30 minutes after prostatic massage. Total PSA
(tPSA), free PSA (fPSA), and cPSA levels were measured using a chemiluminescent enzyme
immunoassay.
Results
After prostatic massage, the tPSA and fPSA levels and fPSA/tPSA ratio increased significantly
(P <0.0001), and the increase in cPSA was minimal but statistically significant (P = 0.047). In patients with prostate cancer, no significant increase occurred in the
mean forms of PSA (tPSA, cPSA, and fPSA/tPSA ratio), except for fPSA, after prostatic
massage. We observed a greater increase in all PSA forms in the chronic prostatitis
group.
Conclusions
In this study, prostatic massage increased serum cPSA concentration, but to a lesser
extent than tPSA and fPSA.
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Article info
Publication history
Accepted:
June 10,
2005
Received:
March 22,
2005
Identification
Copyright
© 2005 Elsevier Inc. Published by Elsevier Inc. All rights reserved.
