This paper adds to the increasing data on the use of ESWT in the management of Peyronie’s
disease. In this study, 42 patients were studied and were divided into two arms: one
group treated on three occasions each separated by 4 weeks and the other group receiving
the three treatments on an every-other-day basis. At each session, each patient received
3000 shocks to the plaque, which was localized using ultrasonography. At a 2-month
follow-up interval, those patients who reported improvement or wanted to receive additional
treatment received another three sessions of ESWT. This noncontrolled study demonstrated
that 14% of men had an excellent outcome in symptoms (defined for the purposes of
this analysis as curvature and pain), and 50% had a significant improvement in symptoms.
Of the men who complained of pain before therapy, 84% reported complete or near-complete
relief of pain after therapy. In this small group of patients, it appeared that the
magnitude of curvature at baseline was not a predictor of improvement in symptoms,
and a longer duration of Peyronie’s disease appeared to be predictive of improvement
(responders had a disease duration of an average of 6 months longer than did nonresponders).
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© 2002 Elsevier Science Inc. Published by Elsevier Inc. All rights reserved.
