Urology
Volume 54, Issue 6 , Pages 956-959 , December 1999

Advances in nerve sparing for radical prostatectomy

  • Laurence Klotz

      Affiliations

    • Division of Urology, Sunnybrook and Women’s Health Science Center, University of Toronto, Toronto, Ontario, Canada
    • L. Klotz has in the past received funding from Uromed Corporation for research projects.
    • Corresponding Author InformationReprint requests: Laurence Klotz, M.D., Division of Urology, Sunnybrook and Women’s Health Science Center, University of Toronto, 2075 Bayview Avenue, MG-408, Toronto, Ontario M4N 3M5, Canada

Received 2 June 1999 ,Revised 22 July 1999 ,Accepted 22 July 1999.

References 

  1. Walsh PC, Donker PJ. Impotence following radical prostatectomy (insight into etiology and prevention). J Urol. 1982;128:492–496
  2. Quinlan DM, Epstein JI, Carter BS, et al.  Sexual function following radical prostatectomy—influence of preservation of neurovascular bundles. J Urol. 1991;145:998–1002
  3. Walsh P: Anatomic radical retropubic prostatectomy, in Campbell’s Urology. 7th ed. Philadelphia, WB Saunders, 1998, pp 2568–2588.
  4. AUA Prostate Cancer Clinical Guidelines Panel report on the management of clinically localized prostate cancer. Baltimore, American Urological Association, 1995, p A-20.
  5. Prostate Disease Patient Outcome Research Team Wasson JH, Cushman CC, Bruskewitz RC, et al.  A structured literature review of treatment for localized prostate cancer. Arch Fam Med. 1993;2:487–493
  6. Robinson JW, Dufour MS, Fung TS. Erectile functioning of men treated for prostate cancer. Cancer. 1997;79:538–544
  7. Klein LT, Miller MI, Buttyan R, et al.  Apoptosis in the rat penis after penile denervation. J Urol. 1997;158:626–630
  8. Montorsi F, Guazzoni G, Barbieri L, et al.  Recovery of spontaneous erectile function after nerve sparing radical prostatectomy with and without early intracavernous injections of prostaglandin E1. Results of a prospective randomized trial. J Urol. 1997;158:1408–1410
  9. Zvara P, Spiess PE, Merlin SL, et al.  Neurogenic erectile dysfunction (the course of nicotinamide adenine dinucleotide phosphate diaphorase-positive nerve fibers on the surface of the prostate). Urology. 1996;47:146–151
  10. Lue TF, Gleason CA, Grock GB, et al.  Intra-operative electrostimulation of the cavernous nerve (technique, results and limitations). J Urol. 1995;154:1426–1428
  11. Bennet CJ, Seager SW, Vasher EA, et al.  Sexual dysfunction and electroejaculation in men with spinal cord injury (review). J Urol. 1988;139:453–457
  12. Creed KE, Carati CJ, Keogh EJ. Autonomic control and vascular changes during penile erection in monkeys. Br J Urol. 1988;61:510–515
  13. Lue TL, Fahey MR, Lin SN, et al.  Effects of anesthesia on penile erection. Surg Forum. 1984;35:628–630
  14. Lue TF, Schmidt RA, Tanagho EA. Electrostimulation and penile erection. Urol Int. 1985;40:60–64
  15. Mueller SC, Aboseif S, Fahey MR, et al.  Spinal anesthesia and electroerection in dogs and monkeys. J Urol. 1989;142:171–175
  16. Shafik A. Cavernous nerve stimulation through an extrapelvic subpubic approach (role in penile erection). Eur Urol. 1994;26:98–102
  17. Steers WD, Mallory B, de Groat WC. Electrophysiological study of neural activity in penile nerve of the rat. Am J Physiol. 1998;254(Pt 2):R989–R1000
  18. Rehman J, Christ G, Melman A, et al.  Intracavernous pressure responses to physical and electrical stimulation of the cavernous nerve in rats. Urology. 1998;51:640–643
  19. Watson DL, Richie JP, Vickers MA, et al.  Cavernosal nerve stimulation during radical retropubic prostatectomy. J Urol. 1995;153:620;(abstract)
  20. Klotz LH, Herschorn S. Early experience with intraoperative cavernous nerve mapping during radical prostatectomy. Urology. 1998;52:537–542
  21. Klotz LH, Jewett MAJ, Heaton J, et al.  A phase 3 trial of intra-operative cavernous nerve mapping during radical prostatectomy. J Urol. 1999;161:592
  22. Kim ED, Scardino PT, Hampel OZ, et al.  Interposition of sural nerve restores function of cavernous nerves resected during radical prostatectomy. J Urol. 1999;161:188–192
  23. Zippe CD, Kedia AW, Kedia K, et al.  Treatment of erectile dysfunction after radical prostatectomy with sildenafil citrate. Urology. 1998;52:963–966
  24. Zagaja GP, Mhoon DA, Brendler CB. Evaluation of response to sildenafil after radical prostatectomy using a confidential mail survey. J Urol. 1999;161:589–592
  25. Gilbert WB, Cookson MS, Milam DF, et al.  Treatment of erectile dysfunction with oral sildenafil following radical retropubic prostatectomy. J Urol. 1999;161:1376–1378

PII: S0090-4295(99)00344-1

Urology
Volume 54, Issue 6 , Pages 956-959 , December 1999