Urology
Volume 79, Issue 1 , Pages 128-132 , January 2012

Risk Factors for Progressive Deterioration of Semen Quality in Patients With Varicocele

  • Shiou-Sheng Chen

      Affiliations

    • Department of Urology, National Yang-Ming University School of Medicine, Taipei, Taiwan
    • Division of Urology, Taipei City Hospital, Renai Branch, Taipei, Taiwan
    • Corresponding Author InformationReprint requests: Shiou-Sheng Chen, M.D., Ph.D., Division of Urology, Taipei City Hospital, Renai Branch, No. 10 Renai Road, Section 4, Taipei 106, Taiwan
    • ,
  • Li-Kuei Chen

      Affiliations

    • Department of Anesthesiology, National Taiwan University, Taipei, Taiwan

Received 27 May 2011 ,Accepted 30 August 2011.

References 

  1. Jarrow JP . Effects of varicocele on male infertility . Hum Reprod Update . 2001;7:59–64
  2. Zheng Y , Zhang X , Zhou J , et al.  Effects on the ipsilateral testis during progression of experimental varicocele in rat . Med Sci Monit . 2008;14:122–126
  3. Witt MA , Lipshultz LI . Varicocele: a progressive or static lesion? . Urology . 1993;42:541–543
  4. Diamond DA , Zurakowski D , Atala A , et al.  Is adolescent varicocele a progressive disease process? . J Urol . 2004;172:1746–1748
  5. Benoff S , Marmar JL , Hurley IR . Molecular and other predictors for infertility in patients with varicoceles . Front Biosci . 2009;14:3641–3672
  6. Zampieri N , Cervellione RM . Varicocele in adolescents: a 6-year longitudinal and follow-up observational study . J Urol . 2008;180:1653–1656
  7. Kozakowski KA , Gjertson CK , Decastro GJ , et al.  Peak retrograde flow: a novel predictor of persistent, progressive and new onset asymmetry in adolescent varicocele . J Urol . 2009;181:2717–2723
  8. Handel LN , Shetty R , Sigman M . The relationship between varicoceles and obesity . J Urol . 2006;176:2138–2140
  9. Irkilata HC , Yildiz O , Yildirim I , et al.  The vasodilator effect of testosterone on the human internal spermatic vein and its relation to varicocele grade . J Urol . 2008;180:772–776
  10. Cayan S , Shavakhaov S , Kadioğlu A . Treatment of palpable varicocele in infertile men: a meta-analysis to define the best technique . J Androl . 2009;30:33–40
  11. Donkol RH , Salem T . Paternity after varicocelectomy: preoperative sonographic parameters of success . J Ultrasound Med . 2007;26:593–599
  12. Jung A , Strauss P , Lindner HJ , et al.  Influence of moderate cycling on scrotal temperature . Int J Androl . 2008;31:403–407
  13. World Health Organization . In: Laboratory Manual for the Examination of Human Semen and Semen-Cervical Mucus Interaction . 2nd ed.. New York: Cambridge University Publishing Group; 1992;p. 34
  14. Keel BA . Within- and between-subject variation in semen parameters in infertile men and normal semen donors . Fertil Steril . 2006;85:128–134
  15. Spinelli C , Di Giacromo M , Lo Piccolo R , et al.  The role of testicular volume in adolescents with varicocele: the better way and time of surgical treatment . J Urol . 2010;184:1722–1726
  16. Tsao CW , Hsu CY , Chou YC , et al.  The relationship between varicoceles and obesity in a young adult population . Int J Androl . 2009;32:385–390
  17. Paasch U , Grunewald S , Kratzsch J , et al.  Obesity and age affect male fertility potential . Fertil Steril . 2010;94:2898–2901
  18. Paul C , Teng S , Saunders PT . A single, mild, transient scrotal heat stress causes hypoxia and oxidative stress in mouse testes, which induces germ cell death . Biol Reprod . 2009;80:913–919
  19. Levinger U , Gornish M , Gat Y , et al.  Is varicocele prevalence increasing with age? . Andrologia . 2007;39:77–80
  20. Cervellione RM , Corroppolo M , Bianchi A . Subclinical varicocele in the pediatric age group . J Urol . 2008;179:717–719
  21. Zampieri N , Pellegrino M , Ottolenghi A , et al.  Effects of bioflavonoid in the management of subclinical varicocele . Pediatr Surg Int . 2010;26:505–508
  22. Kondo Y , Ishikawa T , Yamaguchi K , et al.  Predictors of improved seminal characteristics by varicocele repair . Andrologia . 2009;41:20–23
  23. Ishikawa T , Fujisawa M . Varicocele ligation on free testosterone levels in infertile men with varicocele . Arch J Androl . 2004;50:443–448
  24. Tanrikut C , Goldstein M . Varicocele repair for treatment of androgen deficiency . Curr Opin Urol . 2010;20:500–502

 Funding Support: This study was supported by a grant from Taipei City Hospital (grant 99002-62-096), Taipei, Taiwan.

PII: S0090-4295(11)02341-7

doi: 10.1016/j.urology.2011.08.063

Urology
Volume 79, Issue 1 , Pages 128-132 , January 2012

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