Urology
Volume 77, Issue 2 , Pages 510.e12-510.e16 , February 2011

The Acute Effects of Increased Intra-abdominal Pressure on Testicular Tissue: An Experimental Study in Pigs

  • Mustafa Okan Istanbulluoglu

      Affiliations

    • Gülhane Military Medical Academy, Department of Urology, Ankara, Turkey
    • ,
  • Mesut Piskin

      Affiliations

    • Gülhane Military Medical Academy, Department of Urology, Ankara, Turkey
    • ,
  • Murat Zor

      Affiliations

    • Gülhane Military Medical Academy, Department of Urology, Ankara, Turkey
    • Corresponding Author InformationReprint requests: Murat Zor, M.D., Department of Urology, Gulhane Military Medical Academy, School of Medicine, 06018 Ankara, Turkey
    • ,
  • Asuman Celik

      Affiliations

    • Ankara Education and Research Hospital, Department of Pathology, Ministry of Health, Ankara, Turkey
    • ,
  • Aysegul Ozgok

      Affiliations

    • Yuksek Ihtisas Educational and Research Hospital, Department of Anesthesiology, Ankara, Turkey
    • ,
  • Mutlu Ates

      Affiliations

    • Gülhane Military Medical Academy, Department of Urology, Ankara, Turkey
    • ,
  • Huseyin Ustun

      Affiliations

    • Ankara Education and Research Hospital, Department of Pathology, Ministry of Health, Ankara, Turkey
    • ,
  • Yasar Ozgok

      Affiliations

    • Gülhane Military Medical Academy, Department of Urology, Ankara, Turkey

Received 26 January 2010 ,Accepted 4 June 2010.

References 

  1. Coombs HC . The mechanism of the regulation of intra-abdominal pressure . Am J Physiol . 1920;61:159–163
  2. Sugrue M . Abdominal compartment syndrome . Curr Opin Crit Care . 2005;11(4):333–338
  3. Schein M , Wittmann DH , Aprahamian CC , Condon RE . The abdominal compartment syndrome: the physiological and clinical consequences of elevated intra-abdominal pressure . J Am Coll Surg . 1995;180:745–753
  4. Barnes GE , Laine GA , Giam PY , Smith EE , Granger HJ . Cardiovascular responses to elevation of intra-abdominal hydrostatic pressure . Am J Physiol . 1985;248:208–213
  5. Burchard KW . Cardiovascular, pulmonary, and renal effects of massively increased intra-abdominal pressure in critically ill patients . Crit Care Med . 1990;18:120
  6. Chang MC , Miller PR , Agostino RJ , Meredith JW . Effects of abdominal decompression on cardiopulmonary function and visceral perfusion in patients with intra-abdominal hypertension . J Trauma Inj Infect Crit Care . 1998;44:440–445
  7. Cullen DJ , Coyle JP , Teplick R , Long MC . () cardiovascular, pulmonary, and renal effects of massively increased intra-abdominal pressure in critically ill patients . Crit Care Med . 1989;17:118–121
  8. Richardson JD , Trinkle JK . Hemodynamic and respiratory alterations with increased intra-abdominal pressure . J Surg Res . 1976;20:401–404
  9. Caldwell CB , Ricotta JJ . Changes in visceral blood flow with elevated intraabdominal pressure . J Surg Res . 1987;43:14–20
  10. Diebel LN , Dulchavsky SA , Wilson RF . Effect of increased intra-abdominal pressure on mesenteric arterial and intestinal mucosal blood flow . J Trauma . 1992;33:45–48
  11. Diebel LN , Wilson RF , Dulchavsky SA , Saxe J . Effect of increased intra-abdominal pressure on hepatic arterial, portal venous, and hepatic microcirculatory blood flow . J Trauma . 1992;33:279–282
  12. Imamoğlu M , Cay A , Unsal MA , Aydin S , Ozdemir O , Karahan C , et al.   The effects of increased intraabdominal pressure on testicular blood flow, oxidative stress markers, and morphology . J Pediatr Surg . 2006;41(6):1118–1124
  13. Johnsen SG . Testicular biopsy score count—a method for registration of spermatogenesis in human testes: normal values and results in 335 hypogonadal males . Hormones . 1970;1:2–25
  14. Schafer M , Krahenbuhl L . Effect of laparoscopy on intra-abdominal blood flow . Surgery . 2001;129(4):385–389
  15. Bergh A , Collin O , Lissbrant E . Effects of acute graded reductions in testicular blood flow on testicular morphology in the adult rat . Biol Reprod . 2001;64:13–20
  16. Sweeney TE , Rozum JS , Desjardins C , Gore RW . Microvascular pressure distribution in the hamster testis . Am J Physiol . 1991;260:H1581–H1589
  17. Nath KA , Norby SM . Reactive oxygen species and acute renal failure . Am J Med . 2000;109(8):655–678
  18. Noiri E , Nakao A , Uchida K , Tsukahara H , Ohno M , Fujita T , et al.   Oxidative and nitrosative stress in acute renal ischemia . Am J Physiol Ren Physiol . 2001;281:F948–F957
  19. Bolcal C , Yildirim V , Doganci S , Sargin M , Aydin A , Eken A , et al.   Protective effects of antioxidant medications on limb ischemia reperfusion injury . J Surg Res . 2007;139:274–279
  20. Shiraishi K , Yoshida K , Naito K . Activation of endothelial nitric oxide synthase in contralateral testis during unilateral testicular torsion in rats . Arch Androl . 2003;49(3):179–190
  21. Moncada S , Palmer RMJ , Higgs EA . Nitric oxide: physiology, pathophysiology and pharmacology . Pharmacol Rev . 1991;43:109–142
  22. Zini A , Abitbol J , Girardi SK , Schulsinger D , Goldstein M , Schlegel PN . Germ cell apoptosis and endothelial nitric oxide synthase (eNOS) expression following ischemia–reperfusion injury to testis . Arch Androl . 1998;41(1):57–65
  23. Chander V , Chopra K . Protective effect of nitric oxide pathway in resveratrol renal ischemia-reperfusion injury in rats . Arch Med Res . 2006;37(1):19–26
  24. Mogilner JG , Lurie M , Coran AG , Nativ O , Shiloni E , Sukhotnik I . Effect of diclofenac on germ cell apoptosis following testicular ischemia–reperfusion injury in a rat . Pediatr Surg Int . 2006;22(1):99–105
  25. Turner TT , Tung KS , Tomomasa H , Wilson LW . Acute testicular ischemia results in germ cell-specific apoptosis in the rat . Biol Reprod . 1997;57:1267–1274
  26. Prillaman HM , Turner TT . Rescue of testicular function after acute experimental torsion . J Urol . 1997;157:340–345

PII: S0090-4295(10)00796-X

doi: 10.1016/j.urology.2010.06.009

Urology
Volume 77, Issue 2 , Pages 510.e12-510.e16 , February 2011

Article Tools

* Image Usage & Resolution