Urology
Volume 76, Issue 1 , Pages 32-38 , July 2010

The Urologist's Role in the Management of Spina Bifida: A Continuum of Care

  • Douglass B. Clayton

      Affiliations

    • Corresponding Author InformationReprint requests: Douglass B. Clayton, Division of Pediatric Urology, Department of Urologic Surgery, Vanderbilt University, 2200 Children's Way, 4102 Doctor's Office Tower, Nashville, TN 37232
    • ,
  • John W. Brock III

References 

  1. Boulet S. Racial/ethnic differences in the birth prevalence of spinal bifida—United States 1995-2005. Morb Mortal Wkly Rep. 2009;57:1409–1413
  2. Fichter MA, Dornseifer U, Henke J, et al. Fetal spinal bifida repair—current trends and prospects of intrauterine neurosurgery. Fetal Diagn Ther. 2008;23:271–286
  3. Richter B, Stegmann K, Roper B, et al. Interaction of folate and homocysteine pathway genotypes evaluated in susceptibility to neural tube defects (NTD) in a German population. J Hum Genet. 2001;46:105–109
  4. MRC, Vitamin Study Research Group. Prevention of neural tube defects: results of the Medical Research Council Vitamin study. Lancet. 1991;338:131–137
  5. CDC. Recommendations for the use of folic acid to reduce the number of cases of spinal bifida and other neural tube defects. Morb Mortal Wkly Rep. 1992;41:1–6
  6. FDA. Food standards: amendment of standards of identity for enriched grain products to require addition of folic acid. Fed Regist. 1996;61:8781–8797
  7. Honein MA, Paulozzi LJ, Mathews TJ, et al. Impact of folic acid fortification of the US food supply on the occurrence of neural tube defects. J Am Med Assoc. 2001;285:2981–2986
  8. Williams LJ, Mai CT, Edmonds LD, et al. Prevalence of spinal bifida and anencephaly during the transition to mandatory folic acid fortification in the United States. Teratology. 2002;66:33–39
  9. Boulet SL, Yang Q, Mai C, et al. Trends in the postfortification prevalence of spinal bifida and anencephaly in the United States. Birth Defects Res A Clin Mol Teratol. 2008;82:527–532
  10. Bowman RM, McLone DG, Grant JA, et al. Spina bifida outcome: a 25-year prospective. Pediatr Neurosurg. 2001;34:114–120
  11. Kunisaki SM, Jennings RW. Fetal surgery. J Intensive Care Med. 2008;23:33–51
  12. Adzick NS, Sutton LN, Crombleholme TM, et al. Successful fetal surgery for spinal bifida. Lancet. 1998;352:1675–1676
  13. Tulipan N, Bruner JP. Myelomeningocele repair in utero: a report of three cases. Pediatr Neurosurg. 1998;28:177–180
  14. Management of Myelomeningocele Trial http://clinicaltrials.gov; 2009; NCT00060606.
  15. Holmes NM, Nguyen HT, Harrison MR, et al. Fetal intervention for myelomeningocele: effect on postnatal bladder function. J Urol. 2001;166:2383–2386
  16. Holzbeierlein J, Pope JI, Adams MC, et al. The urodynamic profile of myelodysplasia in childhood with spinal closure during gestation. J Urol. 2000;164:1336–1339
  17. Koh CJ, DeFilippo RE, Borer JG, et al. Bladder and external urethral sphincter function after prenatal closure of myelomeningocele. J Urol. 2006;176:2232
  18. Stoneking BJ, Brock JW, Pope JC, et al. Early evolution of bladder emptying after myelomeningocele closure. Urology. 2001;58:767–771
  19. Edelstein RA, Bauer SB, Kelly MD, et al. Long-term urological response of neonates with myelodysplasia treated proactively with intermittent catheterization and anticholinergic therapy. J Urol. 1995;154:1500
  20. Kaefer M, Pabby A, Kelly M, et al. Improved bladder function after prophylactic treatment of the high risk neurogenic bladder in newborns with myelomentingocele. J Urol. 1999;162:1068–1071
  21. Bauer SB, Hallett M, Khoshbin S, et al. Predictive value of urodynamic evaluation in newborns with myelodysplasia. J Am Med Assoc. 1984;252:650–652
  22. Teichman JM, Scherz HC, Kim KD, et al. An alternative approach to myelodysplasia management: aggressive observation and prompt intervention. J Urol. 1994;152:807–811
  23. Hopps CV, Kropp KA. Preservation of renal function in children with myelomeningocele managed with basic newborn evaluation and close followup. J Urol. 2003;169:305–308
  24. Kessler TM, Lackner J, Kiss G, et al. Early proactive management improves upper urinary tract function and reduces the need for surgery in patients with myelomeningocele. Neurourol Urodyn. 2006;25:758–762
  25. Abrahamsson K, Olsson I, Sillen U. Urodynamic findings in children with myelomeningocele after untethering of the spinal cord. J Urol. 2007;177:331–334Discussion:334
  26. Tarcan T, Bauer S, Olmedo E, et al. Long-term followup of newborns with myelodysplasia and normal urodynamic findings: is followup necessary?. J Urol. 2001;165:564–567
  27. Tarcan T, Onol FF, Ilker Y, et al. Does surgical release of secondary spinal cord tethering improve the prognosis of neurogenic bladder in children with myelomeningocele?. J Urol. 2006;176:1601–1606Discussion:1606
  28. Bowman RM, Ito J, Seibly JM, McLone DG. Tethered cord release: a long-term study in 114 patients. J Neurosurg Pediatr. 2009;3:181–187
  29. Herman J, Mclone D, Storrs B, et al. Analysis of 153 patients with myelomeningocele or spinal lipoma reoperated upon for a tethered cord (Presentation, management, and outcome). Pediatr Neurosurg. 1993;19:243–249
  30. Hudgins RJ, Gilreath CL. Tethered spinal cord following repair of myelomeningocele. Neurosurg Focus. 2004;16:E7
  31. Lapides J, Dinoko A, Silber S, et al. Clean, intermittent self-catheterization in the treatment of urinary tract disease. J Urol. 1972;107:458
  32. Dik P, Klijn A, van Gool JD, et al. Early start to therapy preserves kidney function in spinal bifida patients. Eur Urol. 2006;49:908–913
  33. Lemelle JL, Guillemin F, Aubert D, et al. A multicenter evaluation of urinary incontinence management and outcome in spinal bifida. J Urol. 2006;175:208–212
  34. Verpooten C, Buyse G. The neurogenic bladder: medical treatment. Pediatr Nephrol. 2008;23:717–725
  35. Lindehall B, Abrahamsson K, Jodal U, et al. Complications of clean intermittent catheterization in young females with myelomeningocele (10 –19 Years of followup). J Urol. 2007;178:1053–1055
  36. Lindehall B, Abrahamsson K, Hjalmas K, et al. Complications of clean intermittent catheterization in boys and young males with neurogenic bladder dysfunction. J Urol. 2004;172:1686–1688
  37. Campbell JB, Moore KN, Voaklander DC, et al. Complications associated with clean intermittent catheterization in children with spinal bifida. J Urol. 2004;171:2420–2422
  38. Scales CD, Wiener JS. Evaluating outcomes of enterocystoplasty in patients with spinal bifida: a review of the literature. J Urol. 2008;180:2323–2329
  39. Metcalfe PD, Cain MP, Kaefer M, et al. What is the need for additional bladder surgery after bladder augmentation in childhood?. J Urol. 2006;176:1801–1805Discussion:1805
  40. Lendvay TS, Cowan CA, Mitchell MM, et al. Augmentation cystoplasty rates at children's hospitals in the United States: a pediatric health information system database study. J Urol. 2006;176:1716–1720
  41. Snodgrass W, Keefover-Hicks A, Prieto J, et al. Comparing outcomes of slings with versus without enterocystoplasty for neurogenic urinary incontinence. J Urol. 2009;181:2709–2714Discussion:2714-2716
  42. Husmann DA, Rathbun SR. Long-term follow up of enteric bladder augmentations: the risk for malignancy. J Pediatr Urol. 2008;4:381–385Discussion:386
  43. Lopez Pereira P, Moreno VJA, Espinosa L, et al. Enterocystoplasty in children with neuropathic bladders: long-term follow-up. J Pediatr Urol. 2008;4:27–31
  44. Medel R, Ruarte A, Herrera M, et al. Urinary continence outcome after augmentation ileocystoplasty as a single surgical procedure in patients with myelodysplasia. J Urol. 2002;168:1849–1852
  45. Soergel T, Cain M, Misseri R, et al. Transitional cell carcinoma of the bladder following augmentation cystoplasty for the neuropathic bladder. J Urol. 2004;172:1649–1651
  46. Herndon CD, Rink RC, Shaw MB, et al. Experience with non-cycled artificial urinary sphincters. BJU Int. 2004;93:1049–1052
  47. Misseri R, Cain MP, Casale AJ, et al. Small intestinal submucosa bladder neck slings for incontinence associated with neuropathic bladder. J Urol. 2005;174:1680–1682Discussion:1682
  48. Castellan M, Gosalbez R, Labbie A, et al. Bladder neck sling for treatment of neurogenic incontinence in children with augmentation cystosplasty: long-term followup. J Urol. 2005;173:2128–2131
  49. Block CA, Cooper CS, Hawtrey CE. Long-term efficacy of periurethral collagen injection for the treatment of urinary incontinence secondary to myelomeningocele. J Urol. 2003;169:327–329
  50. Snodgrass WT, Elmore J, Adams R. Bladder neck sling and appendicovesicostomy without augmentation for neurogenic incontinence in children. J Urol. 2007;177:1510–1514Discussion:1515
  51. Dave S, Pippi Salle JL, Lorenzo AJ, et al. Is long-term bladder deterioration inevitable following successful isolated bladder outlet procedures in children with neuropathic bladder dysfunction?. J Urol. 2008;179:1991–1996Discussion:1996
  52. Khoury AE, Dave S, Peralta-Del Valle MH, et al. Severe bladder trabeculation obviates the need for bladder outlet procedures during augmentation cystoplasty in incontinent patients with neurogenic bladder. BJU Int. 2008;101:223–226
  53. Mitrofanoff P. Cystostomie continent trans-appendiuclaire dans le traitement des vessies neruologiques. Chir Pediatr. 1980;21:297
  54. Clark T, Pope JC, Adams MC, et al. Factors that influence outcomes of the Mitrofanoff and Malone antegrade continence enema reconstructive procedures in children. J Urol. 2002;168:1537–1540
  55. Casale AJ, Metcalfe PD, Kaefer MA, et al. Total continence reconstruction: a comparison to staged reconstruction of neuropathic bowel and bladder. J Urol. 2006;176:1712–1715
  56. Harris CF, Cooper CS, Hutcheson JC, et al. Appendicovesicostomy: the Mitrofanoff procedure-a 15-year perspective. J Urol. 2000;163:1922–1926
  57. Malone PS, Ransley PG, Keily EM. Preliminary report: the antegrade continence enema. Lancet. 1990;336:1217
  58. Bani-Hani AH, Cain MP, Kaefer M, et al. The Malone antegrade continence enema: single institutional review. J Urol. 2008;180:1106–1110
  59. Yerkes EB, Cain MP, King S, et al. The Malone antegrade continence enema procedure: quality of life and family perspective. J Urol. 2003;169:320–323
  60. Cain MP, Dussinger AM, Gitlin J, et al. Updated experience with the Monti catheterizable channel. Urology. 2008;72:782–785
  61. Moore C, Kogan BA, Parekh A. Impact of urinary incontinence on self-concept in children with spinal bifida. J Urol. 2004;171:1659–1662
  62. Lemelle JL, Guillemin F, Aubert D, et al. Quality of life and continence in patients with spinal bifida. Qual Life Res. 2006;15:1481–1492
  63. Macneily AE, Morrell J, Secord S. Lower urinary tract reconstruction for spinal bifida—does it improve health related quality of life?. J Urol. 2005;174:1637–1643Discussion:1643
  64. Parekh AD, Thomas JC, Trusler L, et al. Prospective evaluation of health related quality of life for pediatric patients with ureteropelvic junction obstruction. J Urol. 2008;180:2171–2175Discussion:2175-2176.
  65. Lorenzo AJ, Chait PG, Wallis MC, et al. Minimally invasive approach for treatment of urinary and fecal incontinence in selected patients with spinal bifida. Urology. 2007;70:568–571
  66. Storm DW, Fulmer BR, Sumfest JM. Laparoscopic robot-assisted appendicovesicostomy: an initial experience. J Endourol. 2007;21:1015–1017
  67. Storm DW, Fulmer BR, Sumfest JM. Robotic-assisted laparoscopic approach for posterior bladder neck dissection and placement of pediatric bladder neck sling: initial experience. Urology. 2008;72:1149–1152
  68. Atala A, Bauer SB, Soker S, et al. Tissue-engineered autologous bladders for patients needing cystoplasty. Lancet. 2006;367:1241–1246
  69. Joseph D, Borer J, DeFilippo R, et al. A phase-2 study - Tengion autologous neo-bladder augment™ (NBA) for augmentation cystoplasty in subjects with neurogenic bladder secondary to spina bifida. J Urol. 181:LB82.
  70. Xiao C-G, Du M-X, Li B, et al. An artificial somatic-autonomic reflex pathway procedure for bladder control in children with spinal bifida. J Urol. 2005;173:2112–2116

PII: S0090-4295(10)00054-3

doi: 10.1016/j.urology.2009.12.063

Urology
Volume 76, Issue 1 , Pages 32-38 , July 2010

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