Urology
Volume 75, Issue 2 , Pages 321-327 , February 2010

Gender-related Differences in Patients With Stage I to III Upper Tract Urothelial Carcinoma: Results From the Surveillance, Epidemiology, and End Results Database

  • Giovanni Lughezzani

      Affiliations

    • Cancer Prognosis and Health Outcomes Unit, University of Montréal Health Center, Montreal, Quebec, Canada
    • Department of Urology, Vita-Salute San Raffaele University, Milan, Italy
    • Department of Pathology, University of Montréal, Montreal, Quebec, Canada
  • ,
  • Maxine Sun

      Affiliations

    • Cancer Prognosis and Health Outcomes Unit, University of Montréal Health Center, Montreal, Quebec, Canada
    • Department of Pathology, University of Montréal, Montreal, Quebec, Canada
  • ,
  • Paul Perrotte

      Affiliations

    • Department of Urology, University of Montréal, Montreal, Quebec, Canada
    • Department of Pathology, University of Montréal, Montreal, Quebec, Canada
  • ,
  • Shahrokh F. Shariat

      Affiliations

    • Cancer Prognosis and Health Outcomes Unit, University of Montréal Health Center, Montreal, Quebec, Canada
    • Department of Pathology, University of Montréal, Montreal, Quebec, Canada
  • ,
  • Claudio Jeldres

      Affiliations

    • Cancer Prognosis and Health Outcomes Unit, University of Montréal Health Center, Montreal, Quebec, Canada
    • Department of Pathology, University of Montréal, Montreal, Quebec, Canada
  • ,
  • Lars Budäus

      Affiliations

    • Cancer Prognosis and Health Outcomes Unit, University of Montréal Health Center, Montreal, Quebec, Canada
    • Department of Pathology, University of Montréal, Montreal, Quebec, Canada
  • ,
  • Mathieu Latour

      Affiliations

    • Cancer Prognosis and Health Outcomes Unit, University of Montréal Health Center, Montreal, Quebec, Canada
    • Department of Pathology, University of Montréal, Montreal, Quebec, Canada
  • ,
  • Hugues Widmer

      Affiliations

    • Department of Urology, University of Montréal, Montreal, Quebec, Canada
    • Department of Pathology, University of Montréal, Montreal, Quebec, Canada
  • ,
  • Alain Duclos

      Affiliations

    • Department of Urology, University of Montréal, Montreal, Quebec, Canada
    • Department of Pathology, University of Montréal, Montreal, Quebec, Canada
  • ,
  • Francois Bénard

      Affiliations

    • Department of Urology, University of Montréal, Montreal, Quebec, Canada
    • Department of Pathology, University of Montréal, Montreal, Quebec, Canada
  • ,
  • Michael McCormack

      Affiliations

    • Department of Urology, University of Montréal, Montreal, Quebec, Canada
    • Department of Pathology, University of Montréal, Montreal, Quebec, Canada
  • ,
  • Francesco Montorsi

      Affiliations

    • Department of Urology, Vita-Salute San Raffaele University, Milan, Italy
    • Department of Pathology, University of Montréal, Montreal, Quebec, Canada
  • ,
  • Pierre I. Karakiewicz

      Affiliations

    • Cancer Prognosis and Health Outcomes Unit, University of Montréal Health Center, Montreal, Quebec, Canada
    • Department of Pathology, University of Montréal, Montreal, Quebec, Canada
    • Corresponding Author InformationReprint requests: Pierre I. Karakiewicz, M.D., F.R.C.S.C., Cancer Prognostics and Health Outcomes Unit, University of Montreal Health Center (CHUM), 1058, rue St-Denis, Montréal, Québec, Canada, H2X 3J4

Received 30 July 2009 ,Accepted 25 September 2009.

References 

  1. Oosterlinck W, Solsona E, van der Meijden AP, et al. EAU guidelines on diagnosis and treatment of upper urinary tract transitional cell carcinoma. Eur Urol. 2004;46:147–154
  2. Munoz JJ, Ellison LM. Upper tract urothelial neoplasms: incidence and survival during the last 2 decades. J Urol. 2000;164:1523–1525
  3. Greenlee RT, Murray T, Bolden S, et al. Cancer statistics, 2000. CA Cancer J Clin. 2000;50:7–33
  4. Zigeuner R, Pummer K. Urothelial carcinoma of the upper urinary tract: surgical approach and prognostic factors. Eur Urol. 2008;53:720–731
  5. Krogh J, Kvist E, Rye B. Transitional cell carcinoma of the upper urinary tract: prognostic variables and post-operative recurrences. Br J Urol. 1991;67:32–36
  6. Hall MC, Womack S, Sagalowsky AI, et al. Prognostic factors, recurrence, and survival in transitional cell carcinoma of the upper urinary tract: a 30-year experience in 252 patients. Urology. 1998;52:594–601
  7. Langner C, Hutterer G, Chromecki T, et al. pT classification, grade, and vascular invasion as prognostic indicators in urothelial carcinoma of the upper urinary tract. Mod Pathol. 2006;19:272–279
  8. Li CC, Chang TH, Wu WJ, et al. Significant predictive factors for prognosis of primary upper urinary tract cancer after radical nephroureterectomy in Taiwanese patients. Eur Urol. 2008;54:1127–1134
  9. Roscigno M, Cozzarini C, Bertini R, et al. Prognostic value of lymph node dissection in patients with muscle-invasive transitional cell carcinoma of the upper urinary tract. Eur Urol. 2008;53:794–802
  10. Brausi MA, Gavioli M, De Luca G, et al. Retroperitoneal lymph node dissection (RPLD) in conjunction with nephroureterectomy in the treatment of infiltrative transitional cell carcinoma (TCC) of the upper urinary tract: impact on survival. Eur Urol. 2007;52:1414–1418
  11. Novara G, De Marco V, Gottardo F, et al. Independent predictors of cancer-specific survival in transitional cell carcinoma of the upper urinary tract: multi-institutional dataset from 3 European centers. Cancer. 2007;110:1715–1722
  12. Mungan NA, Kiemeney LA, van Dijck JA, et al. Gender differences in stage distribution of bladder cancer. Urology. 2000;55:368–371
  13. Mungan NA, Aben KK, Schoenberg MP, et al. Gender differences in stage-adjusted bladder cancer survival. Urology. 2000;55:876–880
  14. Puente D, Malats N, Cecchini L, et al. Gender-related differences in clinical and pathological characteristics and therapy of bladder cancer. Eur Urol. 2003;43:53–62
  15. Scosyrev E, Noyes K, Feng C, et al. Sex and racial differences in bladder cancer presentation and mortality in the US. Cancer. 2009;115:68–74
  16. Micheli A, Ciampichini R, Oberaigner W, et al. The advantage of women in cancer survival: an analysis of EUROCARE-4 data. Eur J Cancer. 2009;45:1017–1027
  17. Fernandez MI, Shariat SF, Margulis V, et al. Evidence-based sex-related outcomes after radical nephroureterectomy for upper tract urothelial carcinoma: results of large multicenter study. Urology. 2009;73:142–146
  18. Greene FL, Page DL, Flemming ID. American Joint Committee on Cancer Staging Manual. New York, NY: Springer Verlag; 2002;
  19. Margulis V, Shariat SF, Matin SF, et al. Outcomes of radical nephroureterectomy: a series from the Upper Tract Urothelial Carcinoma Collaboration. Cancer. 2009;115:1224–1233
  20. Ries LAG, Melbert D, Krapcho M, et al. SEER Cancer Statistics Review, 1975-2004. Bethesda, MD: National Cancer Institute. Based on November 2006 SEER data submission, posted to SEER website. http://seer.cancer.gov/csr/1975-2004/Accessed January 2007
  21. Fine JP, Gray RJ. A proportional hazards model for the subdistribution of a competing risk. J Am Stat Assoc. 1999;94:496–509
  22. Das AK, Carson CC, Bolick D, et al. Primary carcinoma of the upper urinary tract (Effect of primary and secondary therapy on survival). Cancer. 1990;66:1919–1923
  23. Mansson A, Anderson H, Colleen S. Time lag to diagnosis of bladder cancer—influence of psychosocial parameters and level of health-care provision. Scand J Urol Nephrol. 1993;27:363–369
  24. Madeb R, Messing EM. Gender, racial and age differences in bladder cancer incidence and mortality. Urol Oncol. 2004;22:86–92
  25. Horn EP, Tucker MA, Lambert G, et al. A study of gender-based cytochrome P4501A2 variability: a possible mechanism for the male excess of bladder cancer. Cancer Epidemiol Biomarkers Prev. 1995;4:529–533
  26. Gupta R, Paner GP, Amin MB. Neoplasms of the upper urinary tract: a review with focus on urothelial carcinoma of the pelvicalyceal system and aspects related to its diagnosis and reporting. Adv Anat Pathol. 2008;15:127–139
  27. Kang CH, Yu TJ, Hsieh HH, et al. The development of bladder tumors and contralateral upper urinary tract tumors after primary transitional cell carcinoma of the upper urinary tract. Cancer. 2003;98:1620–1626
  28. Mullerad M, Russo P, Golijanin D, et al. Bladder cancer as a prognostic factor for upper tract transitional cell carcinoma. J Urol. 2004;172:2177–2181
  29. Sanderson KM, Cai J, Miranda G, et al. Upper tract urothelial recurrence following radical cystectomy for transitional cell carcinoma of the bladder: an analysis of 1,069 patients with 10-year followup. J Urol. 2007;177:2088–2094
  30. Lucas SM, Svatek RS, Olgin G, et al. Conservative management in selected patients with upper tract urothelial carcinoma compares favourably with early radical surgery. BJU Int. 2008;102:172–176
  31. Bader MJ, Sroka R, Gratzke C, et al. Laser therapy for upper urinary tract transitional cell carcinoma: indications and management. Eur Urol, in press.
  32. Kircher T, Nelson J, Burdo H. The autopsy as a measure of accuracy of the death certificate. N Engl J Med. 1985;313:1263–1269
  33. Albertsen PC, Walters S, Hanley JA. A comparison of cause of death determination in men previously diagnosed with prostate cancer who died in 1985 or 1995. J Urol. 2000;163:519–523
  34. Penson DF, Albertsen PC, Nelson PS, et al. Determining cause of death in prostate cancer: are death certificates valid?. J Natl Cancer Inst. 2001;93:1822–1823

 Pierre I. Karakiewicz has been partially supported by the University of Montréal Urology Associates, Fonds de la Recherche en Santé du Québec, the University of Montréal, Department of Surgery and the University of Montréal Foundation.

 Giovanni Lughezzani and Maxine Sun have contributed equally for the preparation of this manuscript.

PII: S0090-4295(09)02638-7

doi: 10.1016/j.urology.2009.09.048

Urology
Volume 75, Issue 2 , Pages 321-327 , February 2010