Urology
Volume 75, Issue 1 , Pages 207-211 , January 2010

Prostate Histotripsy in an Anticoagulated Model

  • Jeffery C. Wheat

      Affiliations

    • Department of Urology, University of Michigan, Ann Arbor, Michigan
    • ,
  • Timothy L. Hall

      Affiliations

    • Department of Urology, University of Michigan, Ann Arbor, Michigan
    • ,
  • Christopher R. Hempel

      Affiliations

    • Department of Urology, University of Michigan, Ann Arbor, Michigan
    • ,
  • Charles A. Cain

      Affiliations

    • Department of Biomedical Engineering, University of Michigan, Ann Arbor, Michigan
    • ,
  • Zhen Xu

      Affiliations

    • Department of Biomedical Engineering, University of Michigan, Ann Arbor, Michigan
    • ,
  • William W. Roberts

      Affiliations

    • Department of Urology, University of Michigan, Ann Arbor, Michigan
    • Department of Biomedical Engineering, University of Michigan, Ann Arbor, Michigan
    • Corresponding Author InformationReprint requests: William W. Roberts, M.D., Department of Urology, University of Michigan Health System, 3879 Taubman Center, SPC 5330, 1500 E Medical Center Dr, Ann Arbor, MI 48109-5330

Received 2 April 2009 ,Accepted 10 September 2009.

References 

  1. Ruszat R, Seitz M, Wyler SF, et al. Greenlight laser vaporization of the prostate: single-center experience and long-term results after 500 procedures. Eur Urol. 2008;54:901
  2. Tan A, Liao C, Mo Z, et al. Meta-analysis of holmium laser enucleation versus transurethral resection of the prostate for symptomatic obstruction. Br J Surg. 2007;94:1201–1208
  3. Roberts WW, Hall TL, Ives K, et al. Pulsed cavitational ultrasound: a noninvasive technology for controlled tissue ablation (histotripsy) in the rabbit kidney. J Urol. 2006;175:734–738
  4. Kieran K, Hall TL, Parsons JE, et al. Refining histotripsy: defining the parameter space for the creation of nonthermal lesions with high intensity, pulsed focused ultrasound of the in vitro kidney. J Urol. 2007;178:672–676
  5. Xu Z, Raghavan M, Hall TL, et al. High speed imaging of bubble clouds generated in pulsed ultrasound cavitational therapy—histotripsy. IEEE Trans Ultrason Ferroelectr Freq Control. 2007;54:2091–2101
  6. Xu Z, Fowlkes JB, Rothman ED, et al. Controlled ultrasound tissue erosion: the role of dynamic interaction between insonation and microbubble activity. J Acoust Soc Am. 2005;117:424–435
  7. Tran BC, Seo J, Hall TL, et al. Microbubble-enhanced cavitation for noninvasive ultrasound surgery. IEEE Trans Ultrason Ferroelectr Freq Control. 2003;50:1296–1304
  8. Lake AM, Hall TL, Kieran K, et al. Histotripsy: minimally invasive technology for prostatic tissue ablation in an in vivo canine model. Urology. 2008;72:682–686
  9. Roberts WW, Hall TL, Hempel CR, et al. Prostate histotripsy for BPH: initial canine results. In:  Kollias N,  Choi B,  Zeng H,  Malek RS,  Wong BJ,  Ilgner JFR,  Gregory KW,  Tearney GJ,  Marcu L,  Hirschberg H,  Madsen SJ editor. Photonic Therapeutics and Diagnostics V. Bellingham, WA: SPIE; 2009;p. 71611N;Proceedings of SPIE Vol. 7161.
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  16. Elzayat E, Habib E, Elhilali M. Holmium laser enucleation of the prostate in patients on anticoagulant therapy or with bleeding disorders. J Urol. 2006;175:1428–1432
  17. Ruszat R, Wyler S, Forster T, et al. Safety and effectiveness of photoselective vaporization of the prostate (PVP) in patients on ongoing oral anticoagulation. Eur Urol. 2007;51:1031–1038
  18. Evans HE. Miller's Anatomy of the Dog. In: 3rd ed.. Philadelphia, PA: W. B. Saunders; 1993;p. 514–516
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 This research was funded in part by grants from the Wallace H. Coulter Foundation and NIH 1K08DK081656-01.

 William W. Roberts is entitled to royalties from and is an equity holder in Histosonics, LLC, a private firm which has licensed intellectual property that is referenced in this manuscript.

PII: S0090-4295(09)02559-X

doi: 10.1016/j.urology.2009.09.021

Urology
Volume 75, Issue 1 , Pages 207-211 , January 2010

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