Urology
Volume 74, Issue 3 , Pages 561-564 , September 2009

Is Type 2 Diabetes Mellitus a Cause of Severe Erectile Dysfunction in Patients With Metabolic Syndrome?

  • Yilmaz Aslan

      Affiliations

    • Third Department of Urology, Ankara Numune Research and Training Hospital, Ministry of Health, Ankara, Turkey
    • Corresponding Author InformationReprint requests: Yilmaz Aslan, M.D., Third Department of Urology, Ankara Numune Research and Training Hospital, Ministry of Health, 06120, Sihhiye, Ankara, Turkey
    • ,
  • Tezcan Sezgin

      Affiliations

    • Third Department of Urology, Ankara Numune Research and Training Hospital, Ministry of Health, Ankara, Turkey
    • ,
  • Altug Tuncel

      Affiliations

    • Third Department of Urology, Ankara Numune Research and Training Hospital, Ministry of Health, Ankara, Turkey
    • ,
  • Umit Y. Tekdogan

      Affiliations

    • Third Department of Urology, Ankara Numune Research and Training Hospital, Ministry of Health, Ankara, Turkey
    • ,
  • Serdar Guler

      Affiliations

    • Section of Endocrinology and Metabolism Diseases, Department of Internal Medicine, Ankara and Numune Research and Training Hospital, Ministry of Health, Ankara, Turkey
    • ,
  • Ali Atan

      Affiliations

    • Third Department of Urology, Ankara Numune Research and Training Hospital, Ministry of Health, Ankara, Turkey

Received 30 November 2008 ,Accepted 4 February 2009.

References 

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  2. Demir T, Demir O, Kefi A, et al. Prevalence of erectile dysfunction in patients with metabolic syndrome. Int J Urol. 2006;13:385–388
  3. Heidler S, Temml C, Broessner C, et al. Is the metabolic syndrome an independent risk factor for erectile dysfunction?. J Urol. 2007;177:651–654
  4. Bal K, Oder M, Sahin AS, et al. Prevalence of metabolic syndrome and its association with erectile dysfunction among urologic patients: metabolic backgrounds of erectile dysfunction. Urology. 2007;69:356–360
  5. Gunduz MI, Gumus BH, Sekuri C. Relationship between metabolic syndrome and erectile dysfunction. Asian J Androl. 2004;6:355–358
  6. Vlachopoulos C, Rokkas K, Ioakeimidis N, et al. Inflammation, metabolic syndrome, erectile dysfunction, and coronary artery disease: common links. Eur Urol. 2007;52:1590–1600
  7. Meigs JB, Wilson PW, Nathan DM, et al. Prevalence and characteristics of the metabolic syndrome in the San Antonio heart and Framingham offspring studies. Diabetes. 2003;52:2160–2167
  8. Hanley AJ, Festa A, D'Agostino RB, et al. Metabolic and inflammation variable clusters and prediction of type 2 diabetes: factor analysis using directly measured insulin sensitivity. Diabetes. 2004;53:1773–1781
  9. Goldstraw MA, Kirby MG, Bhardwa J, et al. Diabetes and the urologist: a growing problem. BJU Int. 2007;99:513–517
  10. Melman A, Gingell JC. The epidemiology and pathophysiology of erectile dysfunction. J Urol. 1999;161:5–11
  11. Rosen RC, Cappelleri JC, Smith MD, et al. Development and evaluation of an abridged, 5-item version of the international index of erectile function (IIEF-5) as a diagnostic tool for erectile dysfunction. Int J Impot Res. 1999;11:319–326
  12. International Diabetes Federation. The IDF consensus worldwide definition of the metabolic syndrome. http://www.idf.org
  13. Reaven GM. Banting lecture 1988 (Role of insulin resistance in human disease). Diabetes. 1988;37:1595–1607
  14. De Berardis G, Pellegrini F, Franciosi M, et al. QuED (quality of care and outcomes in type 2 diabetes) Study Group Longitudinal assessment of quality of life in patients with type 2 diabetes and self-reported erectile dysfunction. Diab Care. 2005;28:2637–2643
  15. Feldman HA, Goldstein I, Hatzichristou DG, et al. Impotence and its medical and psychosocial correlates: results of the Massachusetts male aging study. J Urol. 1994;151:54–61
  16. Rendell MS, Rajfer J, Wicker PA, et al. Sildenafil Diabetes Study Group Sildenafil for treatment of erectile dysfunction in men with diabetes: a randomized controlled trial. JAMA. 1999;281:421–426
  17. Palumbo PJ. Metabolic risk factors, endothelial dysfunction, and erectile dysfunction in men with diabetes. Am J Med Sci. 2007;334:466–480
  18. McCulloch DK, Young RJ, Prescott RJ, et al. The natural history of impotence in diabetic men. Diabetologia. 1984;26:437–440
  19. Rhoden EL, Ribeiro EP, Riedner CE, et al. Glycosylated haemoglobin levels and the severity of erectile function in diabetic men. BJU Int. 2005;95:615–617
  20. Al-Hunayan A, Al-Mutar M, Kehinde EO, et al. The prevalence and predictors of erectile dysfunction in men with newly diagnosed with type 2 diabetes mellitus. BJU Int. 2007;99:130–134
  21. American Diabetes Association. Standards of medical care in diabetes. Diab Care. 2005;38:4–36
  22. Fowler MJ. Microvascular and macrovascular complications of diabetes. Clin Diab. 2008;26:77–82
  23. Laaksonen DE, Niskanen L, Punnonen K, et al. Testosterone and sex hormone-binding globulin predict the metabolic syndrome and diabetes in middle-aged men. Diab Care. 2004;27:1036–1041
  24. Yeh HC, Wang CJ, Lee YC, et al. Association among metabolic syndrome, testosterone level and severity of erectile dysfunction. Kaohsiung J Med Sci. 2008;24:240–247
  25. Farrell JB, Deshmukh A, Baghaie AA. Low testosterone and the association with type 2 diabetes. Diab Educ. 2008;34:799–806

PII: S0090-4295(09)00398-7

doi: 10.1016/j.urology.2009.02.073

Urology
Volume 74, Issue 3 , Pages 561-564 , September 2009

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