Urology
Volume 74, Issue 2 , Pages 245-250 , August 2009

Interposition Nerve Grafting During Radical Prostatectomy: Cumulative Review and Critical Appraisal of Literature

  • Wesley M. White

      Affiliations

    • Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, Ohio
    • Corresponding Author InformationReprint requests: Wesley M. White, M.D., Section of Laparoscopic and Robotic Urology, Glickman Urological and Kidney Institute, Cleveland Clinic, 9500 Euclid Avenue, A-100, Cleveland, OH 44195
    • ,
  • Edward D. Kim

      Affiliations

    • Division of Urologic Surgery, University of Tennessee Graduate School of Medicine, Knoxville, Tennessee

Received 27 October 2008 ,Accepted 20 December 2008.

References 

  1. Walsh PC, Donker PJ. Impotence following radical prostatectomy: insight into etiology and prevention. J Urol. 1982;128:492–497
  2. Catalona WJ, Carvalhal GF, Mager DE, et al. Potency, continence and complication rates in 1,870 consecutive radical retropubic prostatectomies. J Urol. 1999;162:433–438
  3. Bianco FJ, Scardino PT, Eastham JA. Radical prostatectomy: long-term cancer control and recovery of sexual and urinary function (“trifecta”). Urology. 2005;66:83–94
  4. Turk IA, Deger S, Morgan WR, et al. Sural nerve graft during laparoscopic radical prostatectomy: initial experience. Urol Oncol. 2002;7:191–194
  5. Kaouk JH, Desai MM, Abreu SC, et al. Robotic-assisted laparoscopic sural nerve grafting during radical prostatectomy: initial experience. J Urol. 2003;3:909–912
  6. Rodriguez E, Melamud O, Ahlering TE. Nerve-sparing techniques in open and laparoscopic prostatectomy. Expert Rev Anticancer Ther. 2008;8:475–479
  7. Davidson PJ, van den Ouden D, Schroeder FH. Radical prostatectomy: prospective assessment of mortality and morbidity. Eur Urol. 1996;29:168–173
  8. Kim ED. Sural nerve grafting during radical prostatectomy: techniques and results. In:  Klein EA editors. Current Clinical Urology: Management of Prostate Cancer. 2nd ed.. Totowa, NJ: Humana Press; 2004;p. 411–430
  9. Walsh PC. Nerve grafts are rarely necessary and are unlikely to improve sexual function in men undergoing anatomic radical prostatectomy. Urology. 2001;57:1020–1024
  10. Kim ED, Scardino PT, Hampel O, et al. Interposition of sural nerve restores function of cavernous nerves resected during radical prostatectomy. J Urol. 1999;161:188–192
  11. Sutherland S. Nerve grafting and related methods of nerve repair. In:  Sutherland S editors. Nerve Injuries and Their Repair: A Critical Appraisal. Edinburgh: Churchill Livingstone; 1991;p. 467–497
  12. Mackinnon SE, Dellon AL. Nerve injury and regeneration. In:  Mackinnon SE,  Dellon AL editor. Surgery of the Peripheral Nerve. New York: Thieme Medical Publishers; 1988;p. 140–152
  13. Slawin KM, Canto EI, Shariat SF, et al. Sural nerve interposition grafting during radical prostatectomy. Rev Urol. 2002;4:17–23
  14. Ball RA, Richie JP, Vickers MA. Microsurgical nerve graft repair of the ablated cavernosal nerves in the rate. J Surg Res. 1992;53:280–286
  15. Catalona WJ, Smith DS, Ratliff TL, et al. Detection of organ-confined prostate cancer is increased through prostate-specific antigen-based screening. JAMA. 1993;270:948–954
  16. IJpma FF, Nicolai JP, Meek MF. Sural nerve donor-site morbidity: thirty-four years of follow-up. Ann Plast Surg. 2006;57:391–395
  17. Srougi M, Pereira D, Dall'oglio M. Sexual rehabilitation after radical retropubic prostatectomy: new technique using ilio-inguinal nerve graft. Int Braz J Urol. 2002;28:446–450
  18. Porpiglia F, Ragni F, Terrone C, et al. Is laparoscopic unilateral sural nerve grafting during radical prostatectomy effective in retaining sexual potency?. BJU Int. 2005;95:1267–1271
  19. Zorn KC, Bernstein AJ, Gofrit ON, et al. Long-term functional and oncological outcomes of patients undergoing sural nerve interposition grafting during robot-assisted laparoscopic radical prostatectomy. J Endourol. 2008;22:1005–1012
  20. Mikhail AA, Song DH, Zorn KC, et al. Sural nerve grafting in robotic laparoscopic radical prostatectomy: interim report. J Endourol. 2007;21:1547–1551
  21. Yohannes P, Rotariu P, Pinto P, et al. Comparison of robotic versus laparoscopic skills: is there a difference in the learning curve?. Urology. 2002;60:39–45
  22. Walsh PC, Marschke P, Catalona WJ, et al. Efficacy of first-generation Cavermap to verify location and function of cavernous nerves during radical prostatectomy: a multi-institutional evaluation by experienced surgeons. Urology. 2001;57:491–494
  23. Klotz L. Cavernosal nerve mapping: current data and applications. BJU Int. 2004;93:9–13
  24. Holzbeierlein J, Peterson M, Smith JA. Variability of results of cavernous nerve stimulation during radical prostatectomy. J Urol. 2001;165:108–110
  25. Canto EI, Nath RK, Slawin KM. Cavermap-assisted sural nerve interposition graft during radical prostatectomy. Urol Clin North Am. 2001;28:839–848
  26. Chang DW, Wood CG, Kroll SS, et al. Cavernous nerve reconstruction to preserve erectile function following non-nerve-sparing radical retropubic prostatectomy: a prospective study. Plast Reconstr Surg. 2003;111:1174–1181
  27. Connolly SS, Yoo JJ, Abouheba M, et al. Cavernous nerve regeneration using acellular nerve grafts. World J Urol. 2008;26:333–339
  28. May F, Matiasek K, Vroemen M, et al. GDNF-transduced Schwann cell grafts enhance regeneration of erectile nerves. Eur Urol. 2008;54:1179–1187
  29. Aszmann OC, Korak KJ, Luegmair M, et al. Bridging critical nerve defects through an acellular homograft seeded with autologous Schwann cells obtained from a regeneration neuroma of the proximal stump. J Reconstr Microsurg. 2008;24:151–158
  30. Mulhall JP. Penile rehabilitation following radical prostatectomy. Curr Opin Urol. 2008;18:613–620
  31. Montorsi F, Brock G, Lee J, et al. Effect of nightly versus on-demand vardenafil on Recovery of erectile function in men following bilateral nerve-sparing radical prostatectomy. Eur Urol. 2008;54:924–931
  32. Rosen RC, Cappelleri JC, Gendaro N. The International Index of Erectile Function (IIEF): a state-of-the-science review. Int J Impot Res. 2002;14:226–244
  33. Wood CG, Change D, Kroll S, et al. Erectile function is preserved after non-nerve sparing radical prostatectomy through sural nerve interposition grafting. J Urol. 2000;167(suppl):157
  34. Lue TF. Physiology of penile erection and pathophysiology of erectile dysfunction. In:  Kavoussi LR,  Novick AC,  Partin AW, et al. editor. 9th ed.. Campbell-Walsh Urology. vol. 2:Philadelphia: WB Saunders; 2007;p. 718–749
  35. Menon M, Shrivastava A, Kaul S, et al. Vattikuti Institute prostatectomy: contemporary technique and analysis of results. Eur Urol. 2006;51:648–658
  36. Kadmon D, Nath R, Shariat S, et al. Unilateral interposition sural nerve grafting following ipsilateral neurovascular bundle resection at radical prostatectomy (RP) decreases the time to potency recovery. J Urol. 2001;165(suppl):149
  37. Secin FP, Koppie TM, Scardino PT, et al. Bilateral cavernous nerve interposition grafting during radical retropubic prostatectomy: Memorial Sloan-Kettering Cancer Center experience. J Urol. 2007;177:664–668
  38. Kim ED, Kadmon K, Slawin KM, et al. Bilateral nerve grafts during radical retropubic prostatectomy: An extended follow-up. Urology. 2001;58:983–987
  39. Namiki S, Saito S, Nakagawa H, et al. Impact of unilateral sural nerve graft on Recovery of potency and continence following radical prostatectomy: 3-year longitudinal study. J Urol. 2007;178:212–216
  40. Hanson GR, Borden LS, Backous DD, et al. Erectile function following unilateral cavernosal nerve replacement. Canada J Urol. 2008;15:3990–3993
  41. Sim HG, Kliot M, Lange PH, et al. Two-year outcome of unilateral sural nerve interposition graft after radical prostatectomy. Urology. 2006;68:1290–1294
  42. Nelson BA, Chang SS, Cookson MS, et al. Morbidity and efficacy of genitofemoral nerve grafts with radical retropubic prostatectomy. Urology. 2006;67:789–792
  43. Joffe R, Klotz LH. Results of unilateral genitofemoral nerve grafts with contralateral nerve sparing during radical prostatectomy. Urology. 2007;69:1161–1164
  44. Anastasiadis AG, Benson MC, Rosenwasser MP, et al. Cavernous nerve graft reconstruction during radical prostatectomy or radical cystectomy: Safe and technically feasible. Prostate Cancer Prostatic Dis. 2003;6:56–60
  45. Davis JW, Chang DW, Chevray P, et al. Randomized phase II trial evaluation of erectile function after attempted unilateral cavernous nerve-sparing retropubic radical prostatectomy with versus without unilateral sural nerve grafting for clinically localized prostate cancer. Eur Urol. 2008 Sept 2;Epub
  46. Gontero P. Editorial comment on: randomized phase II trial evaluation of erectile function after attempted unilateral cavernous nerve-sparing retropubic radical prostatectomy with versus without unilateral sural nerve grafting for clinically localized prostate cancer. Eur Urol. 2008 Sept 2;Epub
  47. Burnett AL. Strategies to promote recovery of cavernous nerve function after radical prostatectomy. World J Urol. 2003;20:337–342
  48. Burnett AL. Neuroprotection and nerve grafts in the treatment of neurogenic erectile dysfunction. J Urol. 2003;170:31–34

PII: S0090-4295(09)00124-1

doi: 10.1016/j.urology.2008.12.059

Urology
Volume 74, Issue 2 , Pages 245-250 , August 2009

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