Urology
Volume 72, Issue 2 , Pages 238-241 , August 2008

Association of Prostate Cancer and Manganese Superoxide Dismutase AA Genotype Influenced by Presence of Occult Cancer in Control Group

  • Taro Iguchi

      Affiliations

    • Department of Urology, State University of New York Upstate Medical University, Syracuse, New York
    • Department of Urology, Osaka City University School of Medicine, Osaka, Japan
    • ,
  • Ching Y. Wang

      Affiliations

    • Department of Urology, State University of New York Upstate Medical University, Syracuse, New York
    • ,
  • Nicolas B. Delongchamps

      Affiliations

    • Department of Urology, State University of New York Upstate Medical University, Syracuse, New York
    • ,
  • Robert Sunheimer

      Affiliations

    • Department of Pathology, State University of New York Upstate Medical University, Syracuse, New York
    • ,
  • Tatsuya Nakatani

      Affiliations

    • Department of Urology, Osaka City University School of Medicine, Osaka, Japan
    • ,
  • Gustavo de la Roza

      Affiliations

    • Department of Pathology, State University of New York Upstate Medical University, Syracuse, New York
    • ,
  • Gabriel P. Haas

      Affiliations

    • Department of Urology, State University of New York Upstate Medical University, Syracuse, New York
    • Corresponding Author InformationReprint requests: Gabriel P. Haas, M.D., Department of Urology, State University of New York Upstate Medical University, 750 East Adams Street, Syracuse, NY 13210.

Received 27 February 2008 ,Accepted 12 March 2008.

References 

  1. Haas GP, Delongchamps NB, Jones RF, et al. Needle biopsies on autopsy prostates: Sensitivity of cancer detection based on true prevalence. J Natl Cancer Inst. 2007;99:1484–1489
  2. Thompson IM, Pauler DK, Goodman PJ, et al. Prevalence of prostate cancer among men with a prostate-specific antigen level < or = 4.0 ng per milliliter. N Engl J Med. 2004;350:2239–2246
  3. Holmberg L, Bill-Axelson A, Helgesen F, et al. A randomized trial comparing radical prostatectomy with watchful waiting in early prostate cancer. N Engl J Med. 2002;347:781–789
  4. Jemal A, Siegel R, Ward E, et al. Cancer statistics, 2007. CA Cancer J Clin. 2007;57:43–66
  5. Lichtenstein P, Holm NV, Verkasalo PK, et al. Environmental and heritable factors in the causation of cancer—Analyses of cohorts of twins from Sweden, Denmark, and Finland. N Engl J Med. 2000;343:78–85
  6. Palapattu GS, Sutcliffe S, Bastian PJ, et al. Prostate carcinogenesis and inflammation: Emerging insights. Carcinogenesis. 2005;26:1170–1181
  7. Valko M, Rhodes CJ, Moncol J, et al. Free radicals, metals and antioxidants in oxidative stress-induced cancer. Chem Biol Interact. 2006;160:1–40
  8. Cooke MS, Evans MD, Dizdaroglu M, et al. Oxidative DNA damage: Mechanisms, mutation, and disease. FASEB J. 2003;17:1195–1214
  9. Fridovich I. Superoxide radical and superoxide dismutases. Annu Rev Biochem. 1995;64:97–112
  10. Shimoda-Matsubayashi S, Matsumine H, Kobayashi T, et al. Structural dimorphism in the mitochondrial targeting sequence in the human manganese superoxide dismutase gene: A predictive evidence for conformational change to influence mitochondrial transport and a study of allelic association in Parkinson's disease. Biochem Biophys Res Commun. 1996;226:561–565
  11. Woodson K, Tangrea JA, Lehman TA, et al. Manganese superoxide dismutase (MnSOD) polymorphism, alpha-tocopherol supplementation and prostate cancer risk in the alpha-tocopherol, beta-carotene cancer prevention study (Finland). Cancer Causes Control. 2003;14:513–518
  12. Li H, Kantoff PW, Giovannucci E, et al. Manganese superoxide dismutase polymorphism, prediagnostic antioxidant status, and risk of clinical significant prostate cancer. Cancer Res. 2005;65:2498–2504
  13. Kang D, Lee KM, Park SK, et al. Functional variant of manganese superoxide dismutase (SOD2 V16A) polymorphism is associated with prostate cancer risk in the prostate, lung, colorectal, and ovarian cancer study. Cancer Epidemiol Biomarkers Prev. 2007;16:1581–1586
  14. Choi JY, Neuhouser ML, Barnett M, et al. Polymorphisms in oxidative stress-related genes are not associated with prostate cancer risk in heavy smokers. Cancer Epidemiol Biomarkers Prev. 2007;16:1115–1120
  15. Jones RF, Sunheimer R, Friedman H, et al. Comparison of ante- and post-mortem PSA levels for epidemiological studies. Anticancer Res. 2005;25:1263–1267

 This study was supported by the National Cancer Institute (grant CA097751 to G. P. Haas) and the National Institute on Aging (grant AG021389 to G. P. Haas).

PII: S0090-4295(08)00611-0

doi: 10.1016/j.urology.2008.03.064

Urology
Volume 72, Issue 2 , Pages 238-241 , August 2008

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