Urology
Volume 71, Issue 3 , Pages 372-378 , March 2008

Port Site Metastasis and Tumor Seeding in Oncologic Laparoscopic Urology

  • Octavio A. Castillo

      Affiliations

    • Section of Endourology and Laparoscopic Urology, Department of Urology, Clínica Santa Maria, Santiago de Chile, Chile
    • Department of Urology, Universidad de Chile School of Medicine, Santiago de Chile, Chile
    • Corresponding Author InformationReprint requests: Octavio A. Castillo, M.D., F.A.C.S., Section of Endourology and Laparoscopic Urology, Department of Urology, Clínica Santa María, Avenida Santa María 0500, Providencia, Santiago de Chile 7530234 Chile.
    • ,
  • Gonzalo Vitagliano

      Affiliations

    • Section of Endourology and Laparoscopic Urology, Department of Urology, Clínica Santa Maria, Santiago de Chile, Chile

Received 9 March 2007 ,Accepted 26 October 2007.

References 

  1. Curet MJ. Port site metastases. Am J Surg. 2004;187:705–712
  2. Stewart GD, Tolley DA. What are the oncological risks of minimal access surgery for the treatment of urinary tract cancer?. Eur Urol. 2004;46:415–420
  3. Rassweiler J, Tsivian A, Ravi Kumbar AV, et al. Oncological safety of laparoscopic surgery for urological malignancy: experience with more than 1,000 operations. J Urol. 2003;169:2072–2075
  4. Dobronte Z, Wittman T, Karacsony G. Rapid development of malignant metastases in the abdominal wall after laparoscopy. Endoscopy. 1978;10:127–130
  5. Ramirez PT, Wolf JK, Levenback C. Laparoscopic port-site metastases: etiology and prevention. Gynecol Oncol. 2003;91:179–189
  6. Tsivian A, Sidi A. Port site metastasis in urological laparoscopic surgery. J Urol. 2003;169:1213–1218
  7. Micali S, Celia A, Bove P, et al. Tumor seeding in urological laparoscopy: an international survey. J Urol. 2004;171:2151–2154
  8. Lee BR, Tan BJ, Smith AD. Laparoscopic port site metastases: incidence, risk factors, and potential preventive measures. Urology. 2005;65:639–644
  9. Fornara P. Port metastases: fact or fiction?. Urologe A. 2002;41:113–119
  10. Whelan RL, Lee SW. Review of investigations regarding the etiology of port site tumor recurrence. J Laparoendosc Adv Surg Tech A. 1999;1:1–16
  11. Highshaw RA, Vakar-Lopez F, Jonasch E. Port-site metastasis: the influence of biology. Eur Urol. 2005;47:357–360
  12. Wichmann MW, Huttl TP, Winter H, et al. Immunological effects of laparoscopic vs open colorectal surgery: a prospective clinical study. Arch Surg. 2005;140:692–697
  13. Novitsky YW, Litwin DE, Callery MP. The net immunologic advantage of laparoscopic surgery. Surg Endosc. 2004;18:1411–1419
  14. Ost MC, Tan BJ, Lee BR. Urological laparoscopy: basic physiological considerations and immunological consequences. J Urol. 2005;174:1183–1188
  15. Sylla P, Kirman I, Whelan RL. Immunological advantages of advanced laparoscopy. Surg Clin North Am. 2005;85:1–18
  16. Kuhry E, Jeekel J, Bonjer HJ. Effect of laparoscopy on the immune system. Semin Laparosc Surg. 2004;11:37–44
  17. Ikramuddin S, Lucus J, Ellison EC, et al. Detection of aerosolized cells during carbon dioxide laparoscopy. J Gastrointest Surg. 1998;2:580–583
  18. Jingli C, Rong C, Rubai X. Influence of colorectal laparoscopic surgery on dissemination and seeding of tumor cells. Surg Endosc. 2006;20:1759–1761
  19. Tsivian A, Shtabsky A, Issakov J, et al. The effect of pneumoperitoneum on dissemination and scar implantation of intra-abdominal tumor cells. J Urol. 2000;164:2096–2098
  20. Burns JM, Matthews BD, Pollinger HS, et al. Effect of carbon dioxide pneumoperitoneum and wound closure technique on port site tumor implantation in a rat model. Surg Endosc. 2005;19:441–447
  21. Halpin VJ, Underwood RA, Ye D, et al. Pneumoperitoneum does not influence trocar site implantation during tumor manipulation in a solid tumor model. Surg Endosc. 2005;19:1636–1640
  22. Gupta A, Watson DI, Ellis T, et al. Tumour implantation following laparoscopy using different insufflation gases. ANZ J Surg. 2002;72:254–257
  23. Mutter D, Hajri A, Tassetti V, et al. Increased tumor growth and spread after laparoscopy vs laparotomy: influence of tumor manipulation in a rat model. Surg Endosc. 1999;13:365–370
  24. Lee SW, Whelan RL, Southall JC, et al. Abdominal wound tumor recurrence after open and laparoscopic assisted Splenectomy in a murine model. Dis Colon Rectum. 1998;41:824–831
  25. Lee SW, Gleason NR, Bessler M, et al. Port site tumor recurrence rates in a murine model of laparoscopic splenectomy decreased with increased experience. Surg Endosc. 2000;14:805–811
  26. Bishoff JT. Laparoscopic radical nephrectomy: morcellate or leave intact?. Definitely morcellate! Rev Urol. 2002;4:34–37
  27. Varkarakis I, Rha K, Hernandez F, et al. Laparoscopic specimen extraction: morcellation. BJU Int. 2005;95(suppl 2):27–31
  28. Meng MV, Miller TR, Cha I. Cytology of morcellated renal specimens: significance in diagnosis and dissemination. J Urol. 2003;169:45–48
  29. Shalhav AL, Leibovitch I, Lev R, et al. Is laparoscopic radical nephrectomy with specimen morcellation acceptable cancer surgery?. J Endourol. 1998;12:255–257
  30. Iwamura M, Tsumura H, Matsuda D, et al. Port site recurrence of renal cell carcinoma following retroperitoneoscopic radical nephrectomy with manual extraction without using entrapment sac or wound protector. J Urol. 2004;171:1234–1235
  31. Whelan RL, Lee SW. Review of investigations regarding the etiology of port site tumor recurrence. J Laparoendosc Adv Surg Tech A. 1999;1:1–16
  32. Stolla V, Rossi D, Bladou F, et al. Subcutaneous metastasis after coelioscopic lymphadenectomy for vesical urothelial carcinoma. Eur Urol. 1994;26:342–343
  33. Andersen JR, Steven K, Smith AD. Implantation metastasis after laparoscopic biopsy of bladder cancer. J Urol. 1995;153:1047–1048
  34. Bangma C, Kirkels WJ, Chadha S, et al. Cutaneous metastasis following laparoscopic pelvic lymphadenectomy for prostatic carcinoma. J Urol. 1995;153:1635–1636
  35. Altieri V, D’Armiento M, Desio M, et al. Can laparoscopic lymphadenectomy disseminate bladder cancer?. Acta Urol Ital. 1998;12:231–233
  36. Ahmed I, Shaikh NA, Kapadia CR. Track recurrence of renal pelvic transitional cell carcinoma after laparoscopic nephrectomy. Br J Urol. 1998;81:319
  37. Otani M, Irie S, Tsuji Y. Port site metastasis after laparoscopic nephrectomy: unsuspected transitional cell carcinoma within a tuberculous atrophic kidney. J Urol. 1999;162:486–487
  38. Fentie DD, Barret PH, Taranger LA. Metastatic renal cell carcinoma after laparoscopic radical nephrectomy: long term follow-up. J Endourol. 2000;14:407–411
  39. Landman J, Clayman R. Re: port site tumor recurrences of renal cell carcinoma after videolaparoscopic radical nephrectomy. (letter) J Urol. 2001;166:629–630
  40. Castilho LN, Fugita OEH, Mitre AI, et al. Port site tumor recurrences of renal cell carcinoma after videolaparoscopic radical nephrectomy. J Urol. 2001;165:519
  41. Wang PH, Yen MS, Juang CM, et al. Intraperitoneal cancer spread after laparoscopic cystectomy for mature teratoma with malignant transformation. Eur J Gynaecol Oncol. 2002;23:131–132
  42. Ong AM, Bhayani SB, Pavlovich C. Trocar site recurrence after laparoscopic nephroureterectomy. J Urol. 2003;170:1301
  43. Chen YT, Yang SSD, Hsieh CH, et al. Hand port-site metastasis of renal-cell carcinoma following hand-assisted laparoscopic radical nephrectomy: case report. J Endourol. 2003;17:771–774
  44. Matsui Y, Ohara H, Ichioka K, et al. Abdominal wall metastasis after retroperitoneoscopic assisted total nephrorureterectomy for renal pelvic cancer. J Urol. 2004;171:793
  45. El-Tabey NA, Shoma AM. Port site metastases after robot-assisted laparoscopic radical cystectomy. Urology. 2005;66:1110
  46. Dhobada S, Patankar S, Fais F, et al. Port-site metastasis after laparoscopic radical nephrectomy for renal-cell carcinoma: case report. J Endourol. 2006;20:119–122
  47. Kinugasa S, Smith E, Drew PA, et al. Aspirin and indomethacin for the prevention of experimental port-site metastases. Surg Endosc. 2004;18:834–838
  48. Wittich P, Mearadji A, Marquet RL, et al. Irrigation of port sites: prevention of port site metastases?. J Laparoendosc Adv Surg Tech A. 2004;14:125–129
  49. Tjalma WA. Laparoscopic surgery and port-site metastases: routine measurements to reduce the risk. Eur J Gynaecol Oncol. 2003;24:236
  50. Steinert R, Lippert H, Reymond MA. Tumor cell dissemination during laparoscopy: prevention and therapeutic opportunities. Dig Surg. 2002;19:464–472
  51. Agostini A, Mattei S, Ronda I, et al. Prevention of port-site metastasis after laparoscopy. Gynecol Obstet Fertil. 2002;30:878–881
  52. Pross M, Lippert H, Nestler G, et al. Effect of low molecular weight heparin on intra-abdominal metastasis in a laparoscopic experimental study. Int J Colorectal Dis. 2004;19:143–146
  53. Schneider C, Jung A, Reymold MA, et al. Efficacy of surgical measures in preventing port site recurrences in a porcine model. Surg Endosc. 2001;15:121–125

PII: S0090-4295(07)02319-9

doi: 10.1016/j.urology.2007.10.064

Urology
Volume 71, Issue 3 , Pages 372-378 , March 2008

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