Urology
Volume 69, Issue 5 , Pages 805-809, May 2007

Development and Validation of Four-Item Version of Male Sexual Health Questionnaire to Assess Ejaculatory Dysfunction

  • Raymond C. Rosen

      Affiliations

    • New England Research Institutes, Watertown, Massachusetts
    • R. C. Rosen is a paid research consultant for Sanofi-Aventis, Pfizer, Auxilium, and King/Palatin
    • Corresponding Author InformationReprint requests: Raymond C. Rosen, Ph.D., New England Research Institutes, 9 Galen Street, Watertown, MA 02472.
  • ,
  • Joseph A. Catania

      Affiliations

    • Oregon State University, Corvallis, Oregon
    • J. A. Catania is a paid consultant for Sanofi-Aventis
  • ,
  • Stanley E. Althof

      Affiliations

    • Case School of Medicine, Center for Marital and Sexual Health of South Florida, West Palm Beach, Florida
    • S. E. Althof is a paid consultant for Sanofi-Aventis, Auxilium, King/Palatin, J & J, Lilly/ICOS, and Pfizer, and is a speaker for Pfizer and Lilly/ICOS, and has done clinical trials for Boehringer-Ingelheim and J & J
  • ,
  • Lance M. Pollack

      Affiliations

    • University of California, San Francisco, School of Medicine, San Francisco, California
  • ,
  • Michael O’Leary

      Affiliations

    • Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts
    • M. O’Leary is a paid consultant for Sanofi-Aventis and has been provided research funding by GlaxoSmithKline, Lilly/ICOS, National Institutes of Health, and GTX
  • ,
  • Allen D. Seftel

      Affiliations

    • Case School of Medicine, Cleveland, Ohio
    • A. D. Seftel is a paid consultant for Sanofi-Aventis and is a consultant for Pfizer, Lilly/ICOS, Auxilium, Solvay, King Pharma, and GlaxoSmithKline.
  • ,
  • David W. Coon

      Affiliations

    • Arizona State University, Glendale, Arizona

Received 1 November 2006; accepted 20 February 2007.

Objectives

An abridged version of the 25-item Male Sexual Health Questionnaire (MSHQ) was developed and validated (MSHQ-EjD Short Form) for assessing ejaculatory dysfunction (EjD).

Methods

The MSHQ was administered to 1245 men in the Men’s Sexual Health Population Survey, 179 gay/bisexual men in the Urban Men’s Health Study, and 6909 men with lower urinary tract symptoms (LUTS) suggestive of benign prostatic hyperplasia (BPH) in the BPH Registry & Patient Survey. Factor analysis, scale reliability, construct and discriminant validity, and the correlation between the MSHQ-EjD Short Form and the MSHQ ejaculatory function domain were assessed.

Results

Factor loadings of greater than 0.5 were demonstrated for four ejaculatory function items (force, volume, frequency, and delay). The force and volume of ejaculation had the greatest factor loadings (range 0.77 to 0.81), followed by frequency of ejaculation (0.64 and 0.66). These three ejaculatory function items had a high degree of internal consistency (Cronbach alpha ≥0.78) and test-retest reliability (r = 0.72). The three items discriminated between men with none/mild LUTS and those with moderate/severe LUTS (P <0.001). After adjusting for age, depression, and erectile function, the odds ratio for a diagnosis of moderate/severe LUTS was 0.68 (95% confidence interval 0.49 to 0.96; P <0.05). The three items had a correlation coefficient of 0.95 with the 7-item MSHQ ejaculatory function domain. The MSHQ ejaculation bother item, an independent domain, showed moderate correlation with the three ejaculatory function items (r = −0.41 and r = −0.45).

Conclusions

The results of our study have shown that the MSHQ-EjD Short Form, with three ejaculatory function items and one ejaculation bother item, has excellent psychometric properties and should be a useful instrument for assessing EjD in clinical and research settings.

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 The Men’s Sexual Health Population Survey and the BPH Registry & Patient Survey were sponsored by Sanofi-Aventis. The Urban Men’s Health Study was funded by grant AG020419.

PII: S0090-4295(07)00268-3

doi:10.1016/j.urology.2007.02.036

Urology
Volume 69, Issue 5 , Pages 805-809, May 2007