Urology
Volume 69, Issue 2 , Pages 338-342 , February 2007

Long-Term Urinary, Sexual, and Rectal Morbidity in Patients Treated with Iodine-125 Prostate Brachytherapy Followed Up for a Minimum of 5 Years

  • Nelson N. Stone

      Affiliations

    • Department of Urology, Mount Sinai School of Medicine, New York, New York
    • N. N. Stone is the owner of Prologics LLC
    • Corresponding Author InformationReprint requests: Nelson N. Stone, M.D., Department of Urology, Mount Sinai School of Medicine, 1 Timber Trail, Suffern, NY 10901.
    • ,
  • Richard G. Stock

      Affiliations

    • Department of Radiation Oncology, Mount Sinai School of Medicine, New York, New York
    • R.G. Stock is a paid consultant/speaker for CR Bard.

Received 11 June 2006 ,Accepted 4 October 2006.

References 

  1. Stone NN, Stock RG. Permanent seed implantation for localized adenocarcinoma of the prostate. Curr Urol Rep. 2002;3:201–206
  2. Grimm PD, Blasko JC, Sylvester JE, et al. 10-year biochemical (prostate specific antigen) control of prostate cancer with 125I brachytherapy. Int J Radiat Oncol Biol Phys. 2001;51:31–40
  3. Stone NN, Stock RG, Unger P. Intermediate-term biochemical and local control following I-125 brachytherapy for prostate cancer. J Urol. 2005;173:803–807
  4. Schellhammer PF, El-Mahdi AM. Pelvic complications after definitive treatment of prostate cancer by interstitial or external beam irradiation. Urology. 1983;21:451–457
  5. Talcott JA, Clark JC, Stark P, et al. Long-term treatment related complications of brachytherapy for early prostate cancer: a survey of patients previously treated. J Urol. 2001;166:494–499
  6. Stock RG, Stone NN, Wesson MF, et al. A modified technique allowing interactive ultrasound-guided three-dimensional transperineal prostate implantation. Int J Radiat Oncol Biol Phys. 1995;32:219–225
  7. Stone NN, Stock RG, DeWyngaert JK, et al. Prostate brachytherapy: improvements in prostate volume measurements and dose distribution using interactive ultrasound guided implantation and three-dimensional dosimetry. Radiat Oncol Invest. 1995;3:185–195
  8. Stock RG, Stone NN, Lo YC, et al. Post-implant dosimetry for I-125 prostate implants: definitions and factors affecting outcome. Int J Radiat Oncol Biol Phys. 2000;48:899–906
  9. Stock RG, Stone NN, Lo YC. Intraoperative dosimetry representation of the real time ultrasound guided prostate implant. Tech Urol. 2000;6:95–98
  10. Stock RG, Kao J, Stone NN. Penile erection function after permanent radioactive seed implantation for treatment of prostate cancer. J Urol. 2001;165:436–439
  11. Desai J, Stock RG, Stone NN, et al. Acute morbidity following I-125 interstitial implantation of the prostate gland. Radiat Oncol Invest. 1998;6:135–141
  12. Cesaretti J, Stone NN, Stock RG. Urinary symptom flare following I-125 prostate brachytherapy. Int J Radiat Oncol Biol Phys. 2003;56:1085–1092
  13. Merrick GS, Butler WM, Wallner KE, et al. Long-term urinary quality of life after permanent prostate brachytherapy. Int J Radiat Oncol Biol Phys. 2003;56:454–461
  14. Van Gellekom MPR, Moerland MA, Van Vulpen M, et al. Quality of life of patients after permanent prostate brachytherapy in relation to dosimetry. Int J Radiat Oncol Biol Phys. 2005;63:772–780
  15. Stone NN, Stock RG. Complications following permanent prostate brachytherapy. Eur Urol. 2002;41:427–433
  16. Merrick GS, Butler WM, Wallner KE, et al. Effects of transurethral resection on urinary quality of life after permanent prostate brachytherapy. Int J Radiat Oncol Biol Phys. 2004;58:81–88
  17. Merrick GS, Butler WM, Wallner KE, et al. Erectile function after permanent prostate brachytherapy. Int J Radiat Oncol Biol Phys. 2002;52:893–902
  18. Hu K, Wallner K. Clinical course of rectal bleeding following I-125 prostate brachytherapy. Int J Radiat Oncol Biol Phys. 1998;41:263–265
  19. Gelblum DY, Potters L. Rectal complications associated with transperineal interstitial brachytherapy for prostate cancer. Int J Radiat Oncol Biol Phys. 2000;48:119–124
  20. Merrick GS, Butler WM, Wallner KE, et al. Late rectal function after prostate brachytherapy. Int J Radiat Oncol Biol Phys. 2003;57:42–48

PII: S0090-4295(06)02338-7

doi: 10.1016/j.urology.2006.10.001

Urology
Volume 69, Issue 2 , Pages 338-342 , February 2007

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