Urology
Volume 68, Issue 3, Supplement , Pages 6-16 , September 2006

Research instruments for the diagnosis and treatment of patients with erectile dysfunction

  • Raymond C. Rosen

      Affiliations

    • Robert Wood Johnson Medical School, Piscataway, New Jersey, USA
    • Raymond C. Rosen is a paid consultant to, and study investigator funded by, Pfizer Inc.
    • Corresponding Author InformationReprint requests: Raymond C. Rosen, PhD, Department of Psychiatry, Center for Sexual and Marital Health, UMDNJ–Robert Wood Johnson Medical School, 125 Old Chemistry Building, Piscataway, NJ 08854-5635.
  • ,
  • Stanley E. Althof

      Affiliations

    • Center for Marital and Sexual Health of South Florida, West Palm Beach, Florida, USA
    • Stanley E. Althof and François Giuliano are paid consultants to, meeting participants and lecturers for, and study investigators partially funded by, Pfizer Inc.
  • ,
  • François Giuliano

      Affiliations

    • Hôpital de Bicêtre, Cedex, France.
    • Stanley E. Althof and François Giuliano are paid consultants to, meeting participants and lecturers for, and study investigators partially funded by, Pfizer Inc.

References 

  1. Rosen RC . Measurement of male and female sexual dysfunction . Curr Psychiatry Rep . 2001;3:182–187
  2. NIH Consensus Conference NIH Consensus Development Panel on Impotence . Impotence . JAMA . 1993;270:83–90
  3. Rosen RC , Riley A , Wagner G , et al.   The International Index of Erectile Function (IIEF): a multidimensional scale for assessment of erectile dysfunction . Urology . 1997;49:822–830
  4. Rosen RC , Cappelleri JC , Gendrano N . The International Index of Erectile Function (IIEF): a state-of-the-science review . Int J Impot Res . 2002;14:226–244
  5. Hultling C , Giuliano F , Quirk F , et al.   Quality of life in patients with spinal cord injury receiving Viagra (sildenafil citrate) for the treatment of erectile dysfunction . Spinal Cord . 2000;38:363–370
  6. Lowentritt BH , Scardino PT , Miles BJ , et al.   Sildenafil citrate after radical retropubic prostatectomy . J Urol . 1999;162:1614–1617
  7. Montorsi F , McDermott TED , Morgan R , et al.   Efficacy and safety of fixed-dose oral sildenafil in the treatment of erectile dysfunction of various etiologies . Urology . 1999;53:1011–1018
  8. Conti CR , Pepine CJ , Sweeney M . Efficacy and safety of sildenafil citrate in the treatment of erectile dysfunction in patients with ischemic heart disease . Am J Cardiol . 1999;83:29C–34C
  9. Seidman SN , Roose SP , Menza MA , et al.   Treatment of erectile dysfunction in men with depressive symptoms: results of a placebo-controlled trial with sildenafil citrate . Am J Psychiatry . 2001;158:1623–1630
  10. Olsson AM , Persson CA . Efficacy and safety of sildenafil citrate for the treatment of erectile dysfunction in men with cardiovascular disease . Int J Clin Pract . 2001;55:171–176
  11. Rendell MS , Rajfer J , Wicker PA , Smith MD  Sildenafil Diabetes Study Group . Sildenafil for treatment of erectile dysfunction in men with diabetes . JAMA . 1999;281:421–426
  12. Goldstein I , Lue TF , Padma-Nathan H , et al.   Oral sildenafil in the treatment of erectile dysfunction . N Engl J Med . 1998;338:1397–1404
  13. Dinsmore WW , Hodges M , Hargreaves C , et al.   Sildenafil citrate (Viagra) in erectile dysfunction: near normalization in men with broad-spectrum erectile dysfunction compared with age-matched healthy control subjects . Urology . 1999;53:800–805
  14. Tan HM , Moh CL , Mendoza JB , et al.  Assess-1 Study Group   Asian sildenafil efficacy and safety study (ASSESS-1): a double-blind, placebo-controlled, flexible-dose study of oral sildenafil in Malaysian, Singaporean, and Filipino men with erectile dysfunction . Urology . 2000;56:635–640
  15. Osegbe DN , Shittu OB , Aghaji AE , et al.   Sildenafil citrate (Viagra) for the treatment of erectile dysfunction in Nigerian men . Int J Impot Res . 2003;15(suppl 1):S15–S18
  16. Levinson IP , Khalaf IM , Shaeer KZ , et al.   Efficacy and safety of sildenafil citrate (Viagra) for the treatment of erectile dysfunction in men in Egypt and South Africa . Int J Impot Res . 2003;15(suppl 1):S25–S29
  17. Benchekroun A , Faik M , Benjelloun S , et al.   A baseline-controlled, open-label, flexible dose-escalation study to assess the safety and efficacy of sildenafil citrate (Viagra) in patients with erectile dysfunction . Int J Impot Res . 2003;15(suppl 1):S19–S24
  18. Roth A , Kalter-Leibovici O , Kerbis Y , et al.   Prevalence and risk factors for erectile dysfunction in men with diabetes, hypertension, or both diseases: a community survey among 1,412 Israeli men . Clin Cardiol . 2003;26:25–30
  19. Becher E , Tejada Noriega A , Gomez R , et al.   Sildenafil citrate (Viagra) in the treatment of men with erectile dysfunction in southern Latin America: a double-blind, randomized, placebo-controlled, parallel-group, multicenter, flexible-dose escalation study . Int J Impot Res . 2002;14(suppl 2):S33–S41
  20. Goldstein I , Carson C , Rosen R , et al.   Vasomax for the treatment of male erectile dysfunction . World J Urol . 2001;19:51–56
  21. Dula E , Keating W , Siami PF , et al.  Apomorphine Study Group   Efficacy and safety of fixed-dose and dose-optimization regimens of sublingual apomorphine versus placebo in men with erectile dysfunction . Urology . 2000;56:130–135
  22. Reiter WJ , Pycha A , Schatzl G , et al.   Dehydroepiandrosterone in the treatment of erectile dysfunction: a prospective, double-blind, randomized, placebo-controlled study . Urology . 1999;53:590–594 discussion 594–595
  23. Mulhall JP , Ahmed A , Branch J , et al.   Serial assessment of efficacy and satisfaction profiles following penile prosthesis surgery . J Urol . 2003;169:1429–1433
  24. Cappelleri JC , Siegel RL , Glasser DB , et al.   Relationship between patient self-assessment of erectile dysfunction and the sexual health inventory for men . Clin Ther . 2001;23:1707–1719
  25. Rosen RC , Cappelleri JC , Smith MD , et al.   Development and evaluation of an abridged, 5-item version of the International Index of Erectile Function (IIEF-5) as a diagnostic tool for erectile dysfunction . Int J Impot Res . 1999;11:319–326
  26. Cappelleri JC , Rosen RC . The Sexual Health Inventory for Men (SHIM): a 5-year review of research and clinical experience . Int J Impot Res . 2005;17:307–319
  27. Cappelleri JC , Siegel RL , Osterloh IH , et al.   Relationship between patient self-assessment of erectile function and the erectile function domain of the international index of erectile function . Urology . 2000;56:477–481
  28. Cappelleri JC , Rosen RC , Smith MD , et al.   Diagnostic evaluation of the erectile function domain of the International Index of Erectile Function . Urology . 1999;54:346–351
  29. Carson CC , Burnett AL , Levine LA , et al.   The efficacy of sildenafil citrate (Viagra) in clinical populations: an update . Urology . 2002;60(suppl 2B):12–27
  30. Meuleman E , Cuzin B , Opsomer RJ , et al.   A dose-escalation study to assess the efficacy and safety of sildenafil citrate in men with erectile dysfunction . BJU Int . 2001;87:75–81
  31. Eardley I , Ellis P , Boolell M , et al.   Onset and duration of action of sildenafil citrate for the treatment of erectile dysfunction . Br J Clin Pharmacol . 2002;53:61S–65S
  32. Olsson AM , Speakman MJ , Dinsmore WW , et al.   Sildenafil citrate (Viagra) is effective and well tolerated for treating erectile dysfunction of psychogenic or mixed aetiology . Int J Clin Pract . 2000;54:561–566
  33. Levinson IP . Erectile function is associated with sexual and relationship satisfaction: a pooled analysis of 26 randomized, double-blind, placebo-controlled trials . [abstract] J Sex Med . 2005;2(suppl 1):59
  34. Cookson MS , Nadig PW . Long-term results with vacuum constriction device . J Urol . 1993;149:290–294
  35. Cappelleri JC , Althof SE , Siegel RL , et al.   Development and validation of the Self-Esteem And Relationship (SEAR) questionnaire in erectile dysfunction . Int J Impot Res . 2004;16:30–38
  36. Althof SE , Cappelleri JC , Shpilsky A , et al.   Treatment responsiveness of the Self-Esteem And Relationship questionnaire in erectile dysfunction . Urology . 2003;61:888–892
  37. O’Leary MP , Althof SE , Cappelleri JC , et al.   Self-esteem, confidence and relationship satisfaction of men with erectile dysfunction treated with sildenafil citrate: a multicenter, randomized, parallel group, double-blind, placebo controlled study in the United States . J Urol . 2006;175:1058–1062
  38. Althof SE , O’Leary MP , Cappelleri JC , et al.   Sildenafil citrate improves self-esteem, confidence, and relationships in men with erectile dysfunction: results from an international, multi-center, double-blind, placebo-controlled trial . J Sex Med . 2006;3:521–529
  39. Montorsi F , Althof S , Sweeney M , et al.   Treatment satisfaction in patients with erectile dysfunction switching from prostaglandin E1 intracavernosal injection therapy to oral sildenafil citrate . Int J Impot Res . 2003;15:444–449
  40. Giuliano F , Montorsi F , Mirone V , et al.  Sildenafil Multicenter Study Group   Switching from intracavernous prostaglandin E1 injections to oral sildenafil citrate in patients with erectile dysfunction: results of a multicenter European study . J Urol . 2000;164:708–711
  41. Jiann BP , Yu CC , Tsai JY , et al.   What to learn about sildenafil in the treatment of erectile dysfunction from 3-year clinical experience . Int J Impot Res . 2003;15:412–417
  42. Althof SE , Turner LA , Levine SB , et al.   Intracavernosal injection in the treatment of impotence: a prospective study of sexual, psychological, and marital functioning . J Sex Marital Ther . 1987;13:155–167
  43. Flynn RJ , Williams G . Long-term follow-up of patients with erectile dysfunction commenced on self injection with intracavernosal papaverine with or without phentolamine . Br J Urol . 1996;78:628–631
  44. Althof SE , Corty EW , Levine SB , et al.   EDITS: development of questionnaires for evaluating satisfaction with treatments for erectile dysfunction . Urology . 1999;53:793–799
  45. Hanson-Divers C , Jackson SE , Lue TF , et al.   Health outcomes variables important to patients in the treatment of erectile dysfunction . J Urol . 1998;159:1541–1547
  46. Eardley I , Wright P , MacDonagh R , et al.   An open-label, randomized, flexible-dose, crossover study to assess the comparative efficacy and safety of sildenafil citrate and apomorphine hydrochloride in men with erectile dysfunction . BJU Int . 2004;93:1271–1275
  47. Lewis R , Bennett CJ , Borkon WD , et al.   Patient and partner satisfaction with Viagra (sildenafil citrate) treatment as determined by the erectile dysfunction inventory of treatment satisfaction questionnaire . Urology . 2001;57:960–965
  48. Sadeghi-Nejad H , Lim H , Long K , et al.   Assessment of the efficacy of Viagra (sildenafil citrate) using the Erectile Dysfunction Inventory of Treatment Satisfaction (EDITS) . Urol Int . 2003;71:100–102
  49. Levine LA , Latchamsetty KC . Treatment of erectile dysfunction in patients with Peyronie’s disease using sildenafil citrate . Int J Impot Res . 2002;14:478–482
  50. Hong EK , Lepor H , McCullough AR . Time dependent patient satisfaction with sildenafil for erectile dysfunction (ED) after nerve-sparing radical retropubic prostatectomy (RRP) . Int J Impot Res . 1999;11:S15–S22
  51. Althof SE . Quality of life and erectile dysfunction . Urology . 2002;59:803–810
  52. Tomlinson J , Wright D . Impact of erectile dysfunction and its subsequent treatment with sildenafil: qualitative study . BMJ . 2004;328:1037–1040
  53. Feldman HA , Goldstein I , Hatzichristou DG , et al.   Impotence and its medical and psychosocial correlates: results of the Massachusetts Male Aging Study . J Urol . 1994;151:54–61
  54. Kaiser DR , Billups K , Mason C , et al.   Impaired brachial artery endothelium-dependent and -independent vasodilation in men with erectile dysfunction and no other clinical cardiovascular disease . J Am Coll Cardiol . 2004;43:179–184
  55. Montorsi F , Padma-Nathan H , Glina S . Erectile function and assessment of erection hardness correlate positively with measures of emotional well-being, sexual satisfaction, and treatment satisfaction in men with erectile dysfunction treated with sildenafil citrate (Viagra®) . Urology . 2006;68(suppl 3A):26–37
  56. Mulhall JP , Levine LA , Jünemann K-P . Erection hardness: a unifying factor for defining response in the treatment of erectile dysfunction . Urology . 2006;68(suppl 3A):17–25
  57. McCullough AR , Carson CC , Hatzichristou D . A prospective study of the beneficial effects of dose optimization and customized instructions on patient satisfaction with sildenafil citrate (Viagra®) for erectile dysfunction . Urology . 2006;68(suppl 3A):38–46

PII: S0090-4295(06)00769-2

doi: 10.1016/j.urology.2006.05.046

Urology
Volume 68, Issue 3, Supplement , Pages 6-16 , September 2006