Urology
Volume 68, Issue 3, Supplement , Pages 38-46 , September 2006

A prospective study of the beneficial effects of dose optimization and customized instructions on patient satisfaction with sildenafil citrate (Viagra®) for erectile dysfunction

  • Andrew R. Mccullough

      Affiliations

    • Department of Urology, New York University School of Medicine, New York, New York, USA
    • Andrew R. McCullough is a member of the medical advisory board for, and receives honoraria and research grants from, Pfizer Inc.
    • Corresponding Author InformationReprint requests: Andrew R. McCullough, MD, Department of Urology, New York University School of Medicine, 150 East 32nd Street, 2nd Floor, New York, NY 10016.
  • ,
  • Culley C. Carson

      Affiliations

    • Division of Urology, Department of Surgery, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA
    • Culley C. Carson is a paid consultant to, meeting participant and lecturer for, and study investigator who is partially funded by, Pfizer Inc.
  • ,
  • Dimitrios Hatzichristou

      Affiliations

    • 2nd Department of Urology, Papageorgiou General Hospital, and Center for Sexual and Reproductive Health, Aristotle University of Thessaloniki, Thessaloniki, Greece.
    • Dimitrios Hatzichristou is a meeting participant and lecturer for Pfizer Inc.

References 

  1. Hatzimouratidis K , Hatzichristou DG . A comparative review of the options for treatment of erectile dysfunction: which treatment for which patient? . Drugs . 2005;65:1621–1650
  2. Goldstein I , Lue TF , Padma-Nathan H , et al.   Oral sildenafil in the treatment of erectile dysfunction . N Engl J Med . 1998;338:1397–1404
  3. Dinsmore WW , Hodges M , Hargreaves C , et al.   Sildenafil citrate (Viagra) in erectile dysfunction: near normalization in men with broad-spectrum erectile dysfunction compared with age-matched healthy control subjects . Urology . 1999;53:800–805
  4. Eardley I , Morgan R , Dinsmore W , et al.   Efficacy and safety of sildenafil citrate in the treatment of men with mild to moderate erectile dysfunction . Br J Psychiatry . 2001;178:325–330
  5. Jiann BP , Yu CC , Tsai JY , et al.   What to learn about sildenafil in the treatment of erectile dysfunction from 3-year clinical experience . Int J Impot Res . 2003;15:412–417
  6. McCullough AR , Barada JH , Fawzy A , et al.   Achieving treatment optimization with sildenafil citrate (Viagra) in patients with erectile dysfunction . Urology . 2002;60:28–38
  7. Atiemo H , Szostak M , Sklar G . Salvage of sildenafil failures referred from primary care physicians . J Urol . 2003;170(pt 1):2356–2358
  8. Jiann BP , Yu CC , Su CC , et al.   Rechallenge prior sildenafil nonresponders . Int J Impot Res . 2004;16:64–68
  9. Hatzichristou D , Moysidis K , Apostolidis A , et al.   Sildenafil failures may be due to inadequate patient instructions and follow-up: a study on 100 non-responders . discussion 522–513 Eur Urol . 2005;47:518–522
  10. McMurray J , Feldman R , Auerbach S , et al.   Long-term effectiveness and tolerability of Viagra (sildenafil citrate) in men with erectile dysfunction . [abstract] Int J Impot Res . 2002;14(suppl 3):S104
  11. Steers W , Guay AT , Leriche A , et al.   Assessment of the efficacy and safety of Viagra (sildenafil citrate) in men with erectile dysfunction during long-term treatment . Int J Impot Res . 2001;13:261–267
  12. Morales A , Gajewski JB , Pommerville PJ , et al.   3-year efficacy and safety of Viagra in men with erectile dysfunction: results of Canadian long-term extension study . [abstract] Can J Urol . 2003;10:1826
  13. Althof SE , Corty EW , Levine SB , et al.   EDITS: development of questionnaires for evaluating satisfaction with treatments for erectile dysfunction . Urology . 1999;53:793–799
  14. Rosen RC , Riley A , Wagner G , et al.   The International Index of Erectile Function (IIEF): a multidimensional scale for assessment of erectile dysfunction . Urology . 1997;49:822–830
  15. Cappelleri JC , Rosen RC , Smith MD , et al.   Diagnostic evaluation of the erectile function domain of the International Index of Erectile Function . Urology . 1999;54:346–351
  16. Wysowski DK , Swann J . Use of medications for erectile dysfunction in the United States, 1996 through 2001 . J Urol . 2003;169:1040–1042
  17. Data on file . New York, NY: Pfizer Inc; 2005;
  18. Marks LS , Duda C , Dorey FJ , et al.   Treatment of erectile dysfunction with sildenafil . Urology . 1999;53:19–24
  19. Jarow JP , Burnett AL , Geringer AM . Clinical efficacy of sildenafil citrate based on etiology and response to prior treatment . J Urol . 1999;162:722–725
  20. Virag R . Indications and early results of sildenafil (Viagra) in erectile dysfunction . Urology . 1999;54:1073–1077
  21. McMahon CG , Samali R , Johnson H . Efficacy, safety and patient acceptance of sildenafil citrate as treatment for erectile dysfunction . J Urol . 2000;164:1192–1196
  22. Harrold LR , Gurwitz JH , Field TS , et al.   The diffusion of a novel therapy into clinical practice: the case of sildenafil . Arch Intern Med . 2000;160:3401–3405
  23. Levinson IP , Stecher VJ , Siegel RL , et al.   Optimal dosing of sildenafil citrate for the treatment of erectile dysfunction: pooled analyses of flexible- and fixed-dose, placebo-controlled, double-blind and open-label extension studies . 2005; Presented at the American Urological Association Annual Meeting; May 21–26, San Antonio, Texas.
  24. Levinson IP , Creanga DL . Appropriate starting dose of VIAGRA® (sildenafil citrate) for the treatment of erectile dysfunction: pooled analysis of flexible-dose, placebo-controlled, double-blind studies and open-label extension . [abstract] J Sex Med . 2005;2(suppl 1):36

PII: S0090-4295(06)00627-3

doi: 10.1016/j.urology.2006.04.040

Urology
Volume 68, Issue 3, Supplement , Pages 38-46 , September 2006