Urology
Volume 67, Issue 6 , Pages 1229-1234 , June 2006

Reliability of small amounts of cancer in prostate biopsies to reveal pathologic grade

  • Christopher R. King

      Affiliations

    • Department of Radiation Oncology, Stanford University School of Medicine, Stanford, California, USA
    • Division of Urologic Oncology, Stanford University School of Medicine, Stanford, California, USA
    • Corresponding Author InformationReprint requests: Christopher R. King, Ph.D., M.D., Department of Radiation Oncology, Stanford University School of Medicine, 875 Blake Wilbur Drive, Stanford, CA 94305-5847.
    • ,
  • John E. McNeal

      Affiliations

    • Department of Urology, Stanford University School of Medicine, Stanford, California, USA
    • Division of Urologic Oncology, Stanford University School of Medicine, Stanford, California, USA
    • ,
  • Harcharan Gill

      Affiliations

    • Department of Urology, Stanford University School of Medicine, Stanford, California, USA
    • Division of Urologic Oncology, Stanford University School of Medicine, Stanford, California, USA
    • ,
  • James D. Brooks

      Affiliations

    • Department of Urology, Stanford University School of Medicine, Stanford, California, USA
    • Division of Urologic Oncology, Stanford University School of Medicine, Stanford, California, USA
    • ,
  • Sandy Srinivas

      Affiliations

    • Department of Medical Oncology, Stanford University School of Medicine, Stanford, California, USA
    • Division of Urologic Oncology, Stanford University School of Medicine, Stanford, California, USA
    • ,
  • Joseph C. Presti Jr

      Affiliations

    • Department of Urology, Stanford University School of Medicine, Stanford, California, USA
    • Division of Urologic Oncology, Stanford University School of Medicine, Stanford, California, USA

Received 26 September 2005 ,Accepted 14 December 2005.

References 

  1. Bostwick DG . Gleason grading of prostate needle biopsies (correlation with grade in 316 matched prostatectomies) . Am J Surg Pathol . 1994;18:796–803
  2. Steinberg DM , Sauvageot BS , Piantadosi S , et al.   Correlation of prostate needle biopsy and radical prostatectomy Gleason grade in academic and community settings . Am J Surg Pathol . 1997;21:566–576
  3. King CR , McNeal JE , Gill H , et al.   Extended prostate biopsy scheme improves reliability of Gleason grading (implications for radiotherapy patients) . Int J Radiat Oncol Biol Phys . 2004;59:386–391
  4. Gleason DF . Histologic grading of prostate cancer (a perspective) . Hum Pathol . 1992;23:273–279
  5. Roach M , DeSilvio M , Lawton C , et al.   Phase III trial comparing whole-pelvic versus prostate-only radiotherapy and neoadjuvant versus adjuvant combined androgen suppression (Radiation Therapy Oncology Group 9413) . J Clin Oncol . 2003;21:1904–1911
  6. Pilepich MV , Caplan R , Byhardt RW , et al.   Phase III trial of androgen suppression using goserelin in unfavorable-prognosis carcinoma of the prostate treated with definitive radiotherapy (report of RTOG 85-31) . J Clin Oncol . 1997;15:1013–1021
  7. Bolla M , Gonsalez D , Warde P , et al.   Improved survival in patients with locally advanced prostate cancer treated with radiotherapy and goserelin . N Engl J Med . 1997;337:295–300
  8. Hanks GE , Pajak TF , Porter A , et al.   Phase III trial of long-term adjuvant androgen deprivation after neoadjuvant hormonal cytoreduction and radiotherapy in locally advanced carcinoma of the prostate (the Radiation Therapy Oncology Group protocol 92-02) . J Clin Oncol . 2003;21:3972–3978
  9. D’Amico AV , Schultz D , Loffredo M , et al.   Biochemical outcome following external beam radiation therapy with or without androgen suppression for clinically localized prostate cancer . JAMA . 2000;284:1280–1283
  10. Freedland SJ , Aronson WJ , Csathy GS , et al.   Comparison of percentage of total prostate needle biopsy tissue with cancer to percentage of cores with cancer for predicting PSA recurrence after radical prostatectomy (results from the SEARCH database) . Urology . 2003;61:742–747
  11. D’Amico AV , Whittington R , Malkowicz SB , et al.   Clinical utility of the percentage of positive prostate biopsies in defining biochemical outcome after radical prostatectomy for patients with clinically localized prostate cancer . J Clin Oncol . 2000;18:1164–1172
  12. Grossklaus DJ , Coffey CS , Shappell SB , et al.   Percent of cancer in the biopsy set predicts pathological findings after prostatectomy . J Urol . 2002;167:2032–2035
  13. Lewis JS , Vollmer RT , Humphrey PA . Carcinoma extent in prostate needle biopsy tissue in the prediction of whole gland tumor volume in a screening population . Am J Clin Pathol . 2002;118:442–450
  14. D’Amico AV , Keshaviah A , Manola J , et al.   Clinical utility of the percentage of positive prostate biopsies in predicting prostate cancer-specific and overall survival after radiotherapy for patients with localized prostate cancer . Int J Radiat Oncol Biol Phys . 2002;53:581–587
  15. Merrick GS , Butler WM , Galbreath RW , et al.   Relationship between percent positive biopsies and biochemical outcome after permanent interstitial brachytherapy for clinically organ-confined carcinoma of the prostate gland . Int J Radiat Oncol Biol Phys . 2002;52:664–673

PII: S0090-4295(05)01785-1

doi: 10.1016/j.urology.2005.12.031

Urology
Volume 67, Issue 6 , Pages 1229-1234 , June 2006

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