Urology
Volume 66, Issue 5 , Pages 1043-1047 , November 2005

Predictors of prostate cancer after initial diagnosis of atypical small acinar proliferation at 10 to 12 core biopsies

  • Vincenzo Scattoni

      Affiliations

    • Department of Urology, “Vita-Salute” University, School of Medicine, San Raffaele Hospital, Milan, Italy
    • Corresponding Author InformationReprint requests: Vincenzo Scattoni, M.D., Department of Urology, “Vita-Salute” University, Scientific Institute H. San Raffaele, Via Olgettina 60, Milan 20132, Italy.
    • ,
  • Marco Roscigno

      Affiliations

    • Department of Urology, “Vita-Salute” University, School of Medicine, San Raffaele Hospital, Milan, Italy
    • ,
  • Massimo Freschi

      Affiliations

    • Department of Pathology, “Vita-Salute” University, School of Medicine, San Raffaele Hospital, Milan, Italy
    • ,
  • Alberto Briganti

      Affiliations

    • Department of Urology, “Vita-Salute” University, School of Medicine, San Raffaele Hospital, Milan, Italy
    • ,
  • Gemma Viola Fantini

      Affiliations

    • Department of Urology, “Vita-Salute” University, School of Medicine, San Raffaele Hospital, Milan, Italy
    • ,
  • Roberto Bertini

      Affiliations

    • Department of Urology, “Vita-Salute” University, School of Medicine, San Raffaele Hospital, Milan, Italy
    • ,
  • Andrea Salonia

      Affiliations

    • Department of Urology, “Vita-Salute” University, School of Medicine, San Raffaele Hospital, Milan, Italy
    • ,
  • Francesco Montorsi

      Affiliations

    • Department of Urology, “Vita-Salute” University, School of Medicine, San Raffaele Hospital, Milan, Italy
    • ,
  • Patrizio Rigatti

      Affiliations

    • Department of Urology, “Vita-Salute” University, School of Medicine, San Raffaele Hospital, Milan, Italy

Received 23 November 2004 ,Accepted 5 May 2005.

References 

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  4. Halushka MK , Kahane H , Epstein JI . Negative 34βE12 staining in a small focus of atypical glands on prostate needle biopsy (a follow-up study of 332 cases) . Hum Pathol . 2004;35:43–46
  5. Iczkowski KA , MacLennan GT , Bostwick DG . Atypical small acinar proliferation suspicious for malignancy in prostate needle biopsies (clinical significance in 33 cases) . Am J Surg Pathol . 1997;21:1489–1495
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  8. Fadare O , Wang S , Mariappan R . Practice patterns of clinicians following isolated diagnoses of atypical small acinar proliferation on prostate biopsy specimens . Arch Pathol Lab Med . 2004;128:557–560
  9. Zhou M , Aydin H , Kanane H , et al.   How often does alpha-methylacyl-coa-racemase contribute to resolving an atypical diagnosis on prostate needle biopsy beyond that provided by basal cell markers? . Am J Surg Pathol . 2004;28:239–243
  10. Roscigno M , Scattoni V , Freschi M , et al.   Monofocal and plurifocal high-grade prostatic intraepithelial neoplasia on extended prostate biopsies (factors predicting cancer detection on extended repeat biopsy) . Urology . 2004;63:1105–1110
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  13. Alsikafi NF , Brendler C , Gerber GS , et al.   High-grade prostatic intraepithelial neoplasia with adjacent atypia is associated with a higher incidence of cancer on subsequent needle biopsy than high-grade prostatic intraepithelial neoplasia alone . Urology . 2001;57:296–300
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  16. Nava L , Montorsi F , Consonni P , et al.   Results of a prospective randomized study comparing 6, 12, and 18 transrectal ultrasound guided sextant biopsies in patients with elevated PSA, normal DRE and normal prostatic ultrasound . J Urol . 1997;157:A226
  17. Moore CK , Karikehalli S , Nazeer T , et al.   Prognostic significance of high-grade prostatic intraepithelial neoplasia and atypical small acinar proliferation in the contemporary era . J Urol . 2005;173:70–72
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PII: S0090-4295(05)00643-6

doi: 10.1016/j.urology.2005.05.006

Urology
Volume 66, Issue 5 , Pages 1043-1047 , November 2005

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