Urology
Volume 61, Issue 1 , Pages 23-29 , January 2003

Management of small renal tumors with radiofrequency ablation

  • Ganesh V Raj

      Affiliations

    • Divisions of Urology, Duke University Medical Center, Durham, North Carolina, USA
  • ,
  • Donal J Reddan

      Affiliations

    • Divisions of Nephrology, Duke University Medical Center, Durham, North Carolina, USA
  • ,
  • Michael B Hoey

      Affiliations

    • Department of Physiology, University of Minnesota School of Medicine, Minneapolis, Minnesota, USA
  • ,
  • Thomas J Polascik

      Affiliations

    • Divisions of Urology, Duke University Medical Center, Durham, North Carolina, USA
    • Corresponding Author InformationReprint requests: Thomas J. Polascik, M.D., Division of Urology, Box 2922, Duke University Medical Center, Central Medical Park, 2609 North Duke Street, Suite 102, Durham, NC 27704, USA

Received 24 May 2001 ,Accepted 20 May 2002.

  • Image Result

    Imaging of RF ablation. (A) Contrast-enhanced computed tomography scan through lower pole of left kidney revealing a 5-cm enhancing mass anteriorly before RF ablation and (B) a somewhat larger, nonenh

    Imaging of RF ablation. (A) Contrast-enhanced computed tomography scan through lower pole of left kidney revealing a 5-cm enhancing mass anteriorly before RF ablation and (B) a somewhat larger, nonenhancing mass of nonviable tissue 1 month after RF ablation.

  • Image Result
    Macroscopic RF ablation. RF electrodes were inserted percutaneously into a human kidney under laparoscopic guidance. An ERBE RF surgical generator (120 W RF, 475 kHz) in the power control mode was use

    Macroscopic RF ablation. RF electrodes were inserted percutaneously into a human kidney under laparoscopic guidance. An ERBE RF surgical generator (120 W RF, 475 kHz) in the power control mode was used and 2 mL/min of 14.6% NaCl solution was infused through an 18-gauge insulated needle with a 1-cm exposed distal tip. The scheduled nephrectomy after RF ablation was performed, and (A) gross lesions are visible on tumor tissue (arrow). The kidney was then fixed in formalin, and the tissues were sectioned and subjected to hematoxylin-eosin histologic examination. (B) Microscopic hematoxylin-eosin staining for RF-treated normal renal tissue. (C) Acute effects of RF ablation on human renal tumors with distinct demarcation between zones of nonablated (dark arrows) and RF-ablated tumor tissue (light arrows).

 T. J. Polascik receives laboratory funding from U.S. Surgical Company; G. V. Raj receives funding from the National Kidney Foundation of North Carolina.

PII: S0090-4295(02)01850-2

Urology
Volume 61, Issue 1 , Pages 23-29 , January 2003