Urology
Volume 43, Issue 4 , Pages 521-524 , April 1994

Relationship between antisperm antibodies and testicular histologic changes in humans after vasectomy

  • Jonathan E. Jarow, M.D.

      Affiliations

    • From the Departments of Urology, the Bowman Gray School of Medicine, Wake Forest University, Winston-Salem, North Carolina, USA
    • Johns Hopkins Hospital, Baltimore, Maryland, USA
    • Department of Urology Bowman Gray School of Medicine Wake Forest University Winston-Salem, North Carolina 27103
    • ,
  • Erik T. Goluboff, M.D.

      Affiliations

    • From the Departments of Urology, the Bowman Gray School of Medicine, Wake Forest University, Winston-Salem, North Carolina, USA
    • Johns Hopkins Hospital, Baltimore, Maryland, USA
    • ,
  • Thomas S.K. Chang, M.D.

      Affiliations

    • From the Departments of Urology, the Bowman Gray School of Medicine, Wake Forest University, Winston-Salem, North Carolina, USA
    • Johns Hopkins Hospital, Baltimore, Maryland, USA
    • ,
  • Fray E. Marshall, M.D.

      Affiliations

    • From the Departments of Urology, the Bowman Gray School of Medicine, Wake Forest University, Winston-Salem, North Carolina, USA
    • Johns Hopkins Hospital, Baltimore, Maryland, USA

Received 2 August 1993 ,Accepted 20 October 1993.

References 

  1. Belker AM, Thomas AJ, Fuchs EF, Konnak JW, Sharlip ID. Results of 1,469 microsurgical vasectomy reversals by the vasovasostomy study group. J Urol. 1991;145:505–511
  2. Sharlip ID. What is the best pregnancy rate that may be expected from vasectomy reversal. J Urol. 1991;145:244A
  3. Fuchs EF, Alexander NJ. Immunologic considerations before and after vasovasostomy. Fertil Steril. 1983;40:497–499
  4. Linnet L, Hjort T, Fogh-Anderson P. Association between failure to impregnate after vasovasostomy and sperm agglutinins in semen. Lancet. 1981;2:117–119
  5. Silber SJ. Pregnancy after vasovasostomy for vasectomy reversal: a study of factors affecting long term return of fertility in 282 patients followed for ten years. Hum Reprod. 1989;4:318–322
  6. Fisch H, Laor E, BarChama N, Witkin SS, Tolia BM, Reid RE. Detection of testicular endocrine abnormalities and their correlation with serum antisperm antibodies in men following vasectomy. J Urol. 1989;141:1129–1132
  7. Esk PC, Pabst R. Improved results of vasovasostomy after sparing of nerves during vasectomy. Fertil Steril. 1981;35:363–364
  8. Dixon JS, Gilpin CJ, Gilpin SA, Gosling JA, Grant JF. The effects of vasectomy on the autonomic innervation of the human vas deferens. J Urol. 1987;137:1014–1016
  9. Gupta AS, Kothari LK, Bapna RB. Surgical sterilization by vasectomy and its effect on the structure and function of the testis in man. Br J Surg. 1975;62:59–63
  10. Jenkins IL, Muir VY, Blacklock NJ, Turk JL, Hanley HG. Consequences of vasectomy: an immunological and histological study related to subsequent fertility. Br J Urol. 1979;51:406–410
  11. Jarow JP, Budin RE, Dym M, Zirkin BR, Noren S, Marshall FF. Quantitative pathologic changes in the human testis after vasectomy, a controlled study. N Engl J Med. 1985;313:1252–1256
  12. Mehrotra R, Nath P, Tandon P, Singh KM, Kumar H. Ultrastructural appearances of interstitial tissue of testis in vasectomised individuals. Indian J Med Res. 1982;77:347–352
  13. Herr JC, Flickinger CJ, Howards SS, Yarbro S, Spell DR, Caloras D, et al. The relation between antisperm antibodies and testicular alterations after vasectomy and vasovasostomy in Lewis rats. Biol Reprod. 1987;37:1297–1305
  14. Flickinger CJ, Howards SS, Carey PO, Spell DR, Kendrick SJ, Caloras D, et al. Testicular alterations are linked to the presence of elevated antisperm antibodies in Sprague-Dawley rats after vasectomy and vasovasostomy. J Urol. 1988;140:627–631
  15. Clarke GN, Stojanoff A, Cauchi MN, Johnson WI. The immunoglobulin class of antispermatozoal antibodies in serum. Am J Reprod Immunol Microbiol. 1985;7:143–147

PII: 0090-4295(94)90246-1

Urology
Volume 43, Issue 4 , Pages 521-524 , April 1994

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