Urology
Volume 8, Issue 5 , Pages 452-454, November 1976

Oxybutynin in bladder spasm, neurogenic bladder, and enuresis

From the Section of Urology, University of Missouri School of Medicine, Columbia, Missouri, USA

Abstract 

Oxybutynin chloride (Ditropan), a tertiary amine possessing anticholinergic and papaverine-like, direct muscular antispasmodic effects, has been used in controlled clinical studies in patients with neurovesical reflex activity, uninhibited bladders, enuresis, and primary muscle spasm. The cystometrically documented, synergistic, anticholinergic, and muscle relaxant activity of oxybutynin observed in these studies indicates that the drug can be highly effective in the mangement of reflex neurovesical dysfunction, enuresis, and bladder spasm.

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PII: 0090-4295(76)90273-9

Urology
Volume 8, Issue 5 , Pages 452-454, November 1976